Objective: To Study 'stasis heat’ index of Taohe Chengqi decoction and its decomposed recipes on rat model with heat and blood stasis syndrome. Method: The ratswere injected with lipopolysaccharide (LPS 50 μg·kg-1) via tail veins at interval of 24 hours to make rat stasis syndrome model. Each group was orally administrated the test drugs or saline after the first injection of LPS for 0.5

12 h and the second injection of LPS for 0.5 h. The dosages of Taohe Chengqi group

Tiaowei group

Tiaotao group

Tiaogui group and Taogui group were respectively 10

5.7

8.6

7.1

4.3 g·kg-1 body weight. Model group and normal control group were given the same volume saline. Blood were collected at last injection. The serum tissue type plasminogen activator(t-PA)

plasminogen activator inhibitor-1(PAI-1)

superoxide dismutase(SOD)

malondialdehyde(MDA)

nitric oxide(NO) and plasma endothelin-1(ET-1)

6-keto- prostagland in F1α(6-keto- F1α)

thromboxane B2(TXB2) were measured. Result: Taohe Chengqi group

Tiao wei group

Tiao tao group and Tiaogui group increased SOD(P<0.01)and decreased MDA(P<0.01). Tao he Cheng qi group

Tiaowei group decreased PAI-1 and t-PA/PAI-1(P<0.01). Tiao wei group

Tiaogui group increased t-PA(P<0.01). Taogui group had no obvious effect on SOD

MDA and PAI-1

but showed significant difference compared with Tao he Cheng qi group. All test drug group increased TXB2

6-Keto-PGF1α/ TXB2 and descended NO. Conclusion: Tao he Cheng qi decoctionon ‘stasis’ and ‘hot’ is superior to other compatibility groups. Tiao wei group has good regulating effects on ‘stasis’ and ‘hot’. Tiao gui group in the regulation of'stasis’was better than Tao he Cheng qi group. Tao gui group was the worst in the regulating effects on ‘stasis’ and ‘heat’.