Chinese Journal of Experimental Traditional Medical FormulaeVol. 19, Issue 3, Pages: 104-107(2013)
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Published:2013
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LIU Xiao-shuan, LI Xi-xiang, ZHANG Xiao-hua, et al. The Quality Standard of Shangke Jiefuye[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 104-107.
DOI:
LIU Xiao-shuan, LI Xi-xiang, ZHANG Xiao-hua, et al. The Quality Standard of Shangke Jiefuye[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 104-107.DOI:
The Quality Standard of Shangke Jiefuye
摘要
目的: 建立伤科洁肤液的质量控制方法
以提高其质量标准。 方法: 采用薄层色谱法对方中主要药味当归、虎杖、黄柏、栀子进行定性鉴别研究
采用HPLC同时测定伤科洁肤液中主要有效成分苦参碱的含量
流动相为乙腈-0.2%磷酸溶液-三乙胺(1∶99∶0.3)
检测波长220 nm。 结果: 薄层色谱定性鉴别的特征斑点清晰
专属性强
Rf值适中
阴性对照无干扰;HPLC测定苦参碱的线性范围为0.434~2.170 μg(r=0.999 1)
加样回收率为97.62%(RSD 1.86%)。 结论: 该方法简便可靠
专属性强
重复性好
能较全面反映该制剂内在质量
可用于该制剂的质量控制。
Abstract
Objective:To establish the way to control the quality of matrine in Shangke Jiefuye. Method: Chinese Angelica
Polygonum cuspidatum
golden cypress and jasmine in the description were identified by TLC. The content of matrine which is the effective substance in the preparation was determined by HPLC with acetonitrile-0.2% phosphoric acid-triethylamine (1∶99∶0.3) as a mobile phase and the detection wavelength was set at 220 nm. Result: Drugs could be detected by TLC. The linear correlation of the matrine is good in extent of 0.434-2.170 μg and the recovery is 97.62% (RSD 1.86%). Conclusion: The quality control is feasible and can be applied to control the products from mass production. It can ensure the stability of the pharmaceutical quality.
Studies on Qualitative and Quantitative Methods of Liangge Pills
Studies on the Quality standard of Bimintong Capsule
Quality Standard Study for Kangan Liyan Capsule
Study on the Quality Standard of Licorice Juice as A Processing Excipient
Related Author
LIU Xiao-shuan
LI Xi-xiang
ZHANG Xiao-hua
CHEN Er-lin
SHI Tao1
2
MENG Xian-sheng2
3
Related Institution
Gansu Province Hospital of Traditional Chinese Medicine
Hubei Institute for Food and Drug Control
Acupuncture and Moxibustion Hospital Affiliated to Anhui College of Traditional Chinese Medicine & Anhui Modern Engineering Technology Research Center of Chinese Medicine