Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 20, Pages: 205-208(2012)
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Published:2012
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WEI Gui-ning, ZENG Xian-biao, YA Qi-kang, et al. Empirical Study of in Treatment of Gout[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 205-208.
DOI:
WEI Gui-ning, ZENG Xian-biao, YA Qi-kang, et al. Empirical Study of in Treatment of Gout[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 205-208.DOI:
Objective:To observe the therapeutic effects of Polyrhachis vicina Roger on gout. Method: Kunming mice and Wistar rats were randomly divided into control group
model group
positive control group
P. vicina low
medium and high dose groups(1
2
4 g·kg-1)
respectively. The anti-gout effects of P. vicina were studied by observing its effects on the level of blood uric acid in hyperuricacidemia mice induced by hypoxanthine and nomal mice
and rat’s foot swelling induced by microcrystalline sodium urate (MSU) after 15 days treatment. Result: Compared to the level of blood uric acid in control group(131.09±45.78) μmol·L-1and model group(198.63±47.27)μmol·L-1
medium(2 g·kg-1) and high dose groups(4 g·kg-1)of P. vicina alcohol extract
and high dose group(4 g·kg-1)water extract could reduce the blood uric acid in model mice
and satisfactory inhibited acute gouty arthritis
relieved rat’s foot welling in model rats induced by MSU in 3 hours.The effects of P. vicina alcohol extract on gout was better than that in water extract. Conclusion: P. vicina could inhibit the level of blood uric acid in hyperuricacidemia mice induced by hypoxanthine and inflammation induced by MSU
which indicates that P. vicina has therapeutic effect on gout.
Effect of Tongfeng Decoction in Treating Gout with Moist Heat and Blood Stasis Syndrome
Experimental Study of Bixie Chubi Tang in Treating Gout
Multi-source Fusion Analysis and Medication Pattern Mining of Clinical Literature on Traditional Chinese Medicine Treatment of Gout
Effect of Huangling Jidu Xizhuo Granules on NLRP3, Intestinal Flora and Short-term Prognosis in Patients with Gout
Pharmacological Effect of Phellodendri Chinensis Cortex and Active Components on Gout: A Review
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Related Institution
Zhejiang Chinese Medical University
The First Affiliated Hospital of Anhui University of Chinese Medicine
Hunan Provincial Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, the "Double-First Class" Application Characteristic Discipline of Hunan Province (Pharmaceutical Science), Changsha Medical University
Sichuan Academy of Chinese Medicine Sciences, Sichuan Center for Translational Chinese Medicine, Key Laboratory of Biological Evaluation of Quality of TCM, State Administration of TCM, Sichuan Key Laboratory of Translational Chinese Medicine, Sichuan Engineering Technology Research Center of Genuine Regional Drug, Sichuan Provincial Engineering Research Center of Formation Principle and Quality Evaluation of Genuine Medicinal Materials
School of Pharmacy, Chengdu University of Traditional Chinese Medicine(TCM)