Influence of Jianpi Bushen Huoxue Fang Treated on Nerve Functional Lack and T Cell Subsets of Cerebral Infarct Patients
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Influence of Jianpi Bushen Huoxue Fang Treated on Nerve Functional Lack and T Cell Subsets of Cerebral Infarct Patients
Chinese Journal of Experimental Traditional Medical FormulaeVol. 19, Issue 3, Pages: 279-282(2013)
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Published:2013
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LIU Xiang-zhe, WANG Xin-zhi, WANG Cong. Influence of Jianpi Bushen Huoxue Fang Treated on Nerve Functional Lack and T Cell Subsets of Cerebral Infarct Patients[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 279-282.
DOI:
LIU Xiang-zhe, WANG Xin-zhi, WANG Cong. Influence of Jianpi Bushen Huoxue Fang Treated on Nerve Functional Lack and T Cell Subsets of Cerebral Infarct Patients[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 279-282.DOI:
Influence of Jianpi Bushen Huoxue Fang Treated on Nerve Functional Lack and T Cell Subsets of Cerebral Infarct Patients
Objective:To evaluate the clinical effect of the Jianpi Bushen Huoxue Fang treated on cerebral infarct and its influence on cell immune function. Method: Sixty patients suffered from cerebral infarct were divided into two average groups including the treatment group and the control group at random
the two groups were both treated with routine western medicine
besides this
the treatment group was dosed the Jianpi Bushen Huoxue Fang additionally which could strengthen body resistance
14 days is a period of treatment
we observed two periods. Assessing the two groups respectively before and after treatment of 7
14
28 days with the national institutes of health storke scale(NIHSS) score
at the same time
the change of the peripheral blood T cell subsets was measured by flow cytometry in both groups before and after treatment. Result: The significance of the treatment group was 76.76% and the total effective rate was 93.33%
while the number was 40.0% and 73.33% in the control group. The curative effect of the treatment group is higher obviously than that of the control group (P<0.01
P<0.05). The NIHSS score after treatment declined obviously in both groups(P<0.01)
and it is much more significant for the treatment group(P<0.01). The number of CD3+
CD4+
CD4+/CD8+ in both groups increased obviously(P<0.01) while the number of CD8+ decreased significantly(P<0.01) after treatment
and the number of CD3+
CD4+
CD4+/CD8+ in treatment group increased much more than control group(P<0.01)
the number of CD8+ also decreased much more than control group(P<0.01). Conclusion: The Jianpi Bushen Huoxue Fang
which has the effect of strengthening body resistance
could improve the clinical symptom and sign of cerebral infarct patients and enhance the function of cell immune