Comparative Study on Anti-inflammatory and Antibacterial Effects of Different Preparation Technology of Gegen Qinlian Decoction
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Comparative Study on Anti-inflammatory and Antibacterial Effects of Different Preparation Technology of Gegen Qinlian Decoction
Chinese Journal of Experimental Traditional Medical FormulaeVol. 19, Issue 1, Pages: 224-226(2013)
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Published:2013
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YANG Jing, YANG Li-zhen, WANG Ya-xian, et al. Comparative Study on Anti-inflammatory and Antibacterial Effects of Different Preparation Technology of Gegen Qinlian Decoction[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(1): 224-226.
DOI:
YANG Jing, YANG Li-zhen, WANG Ya-xian, et al. Comparative Study on Anti-inflammatory and Antibacterial Effects of Different Preparation Technology of Gegen Qinlian Decoction[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(1): 224-226.DOI:
Comparative Study on Anti-inflammatory and Antibacterial Effects of Different Preparation Technology of Gegen Qinlian Decoction
Objective:To study the anti-inflammatory and antibacterial effects of Gegen Qinlian decoction prepared by different technology. Method: The swelling of ear induced by xylene in mice was employed to evaluate the anti-inflammatory effects of Gegen Qinlian decoction prepared by different technology. Additionally
the model of bacteriostasis in vitro by the serum with drug was used to examine the antibacterial activities of those. Result: Compared with mixed decoction and separated decoction
extract of active ingredients (1.95 g·kg-1) strongly inhibited swelling of ear in mice(P<0.01). The serum with extract of active ingredients significantly inhibited 10 kinds of strains such as Escherichia coli
Staphylococcus aureus and Salmonella typhi
etc. (P<0.01). Conclusion: Extract of active ingredients can exert significant inhibitory action against inflammation caused by chemical agents
and the serum with extract of active ingredients also has strong antibacterial activity.