Objective:To observe clinical efficacy and adverse reaction of Cornu Antelopes capsule as adjunctive therapy for partial seizures. Method: The treatment period was six months

89 patients with partial Seizures were chosen that were divided into refractory partial epilepsy (35)and not refractory partial epilepsy(54). Result: Cornu Antelopes capsule produced statistically significant median reduction in seizure frequency as compared with the pre-cornu antelopes capsule period (3 months baseline)

the efficiency was 53.9% for total seizure counts. The efficiency and control rate is 78.8% and 21.2% for not refractory partial epilepsy compared to 18.9% and 0 for refractory partial epilepsy. Conclusion: Cornu Antelopes capsule adjunctive therapy for Partial epilepsy is an effective and safe treatment.