Objective: To study the effects of rhizosphere soil chemical properties on content of chromones and counarins in radix Saposhnikovia divaricata collected from different regions in different harvest times. Method: The HPLC method was adopted for determination content of eight effective components in methanol extracts from radix S. divaricata. According to the National Standard of the People's Republic of China

the pH value

total nitrogen

hydrolysable nitrogen

available phosphorus

potassium and organic matter in rhizosphere soils of S. divaricata were determined. The obtained data were statistical analyzed with SPSS 13.0 software. Result: In general

content of 4 chromones was higher in the first samples than in the second samples and less affected by rhizosphere soils. To the second samples

the soil pH value was significantly negatively correlated to psoralen and xanthotoxin content

but significantly positively correlated to imperatorin content. Whereas

there was a significant positive correlation between soil available phosphorus content and cimicifugin

sec-O-glucosylhamaudol

psoralen

4'-O-β-D-glucosyl-5-O-methylvisamminol

xanthotoxin

bergaptol methyl ether and imperatorin content. Conclusion: Rhizosphere soils had different influence on chromones and counarins content in radix S. divaricata collected in different harvest times

especially the samples collected in October.