Experimental Study on Anti-allergic Effect of Extracts from Seven Kinds of Chinese Herbal Medicine

Li Yang; DONG Yin-mao; MENG Hong; ZHU Jun

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Experimental Study on Anti-allergic Effect of Extracts from Seven Kinds of Chinese Herbal Medicine

更新时间：2024-01-04

- Experimental Study on Anti-allergic Effect of Extracts from Seven Kinds of Chinese Herbal Medicine
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 4, Pages: 191-194(2013)
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- Published：2013
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Li Yang, DONG Yin-mao, MENG Hong, et al. Experimental Study on Anti-allergic Effect of Extracts from Seven Kinds of Chinese Herbal Medicine[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(4): 191-194.
DOI：

Li Yang, DONG Yin-mao, MENG Hong, et al. Experimental Study on Anti-allergic Effect of Extracts from Seven Kinds of Chinese Herbal Medicine[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(4): 191-194. DOI：

摘要

目的: 考查地肤子皂苷、防风多糖、桃仁和金银花水提物、茶多酚、洋甘菊和仙人掌提取物的抗皮肤过敏作用

探究其刺激性大小

为作为具有抗过敏功效化妆品添加剂提供依据。方法: 采用透明质酸酶体外抑制试验和红细胞溶血试验

对7种中草药提取物抗过敏特性及其刺激性进行探究。结果: 7种中草药有效部位或成分的抗过敏抑制率分别为洋甘菊提取物(77.04%)>金银花水提物(69.54%)>茶多酚(68.01%)>仙人掌提取物(62.67%)>防风多糖(55.51%)>地肤子皂苷(43.09%)>桃仁水提物(32.74%);其中只有茶多酚添加浓度超过6 g·L-1时显示出一定的刺激性

其他有效成分的溶血率均低于20%

刺激性很小。结论: 7种中草药有效部位或成分均表现一定的抗过敏特性

且在规定添加量范围内刺激性均很小

适合作为抗过敏化妆品添加剂使用。

Abstract

Objective: To investigate the anti-allergic effect of extracts from Fructus Kochia Scoparia

Saposhnikovia divaricata

Peach seed

Lonicera

tea polyphenols

Chamomile Extractand and Opuntia

to evaluate their irritating effect

and to provide data for the herbal medicine as potential additives in cosmetic. Method: The method of hyaluronidase inhibition in vitro was used to explore the anti-allergic properties of the extracts of the seven Chinese herbal medicine. And hemolysis of red blood cell was used to evaluate their irritating effects. Result: The anti-allergy inhibition rates of the extracts were as following:Chamomile Extract(77.04%)>Lonicera water extract(69.54%)>tea polyphenols(68.01%)>Opuntia extract(62.67%)>S. divaricata(55.51%)>Fructus Kochia Scoparia(43.09%)>Peach seed water extract(32.74%). In the seven extracts

only tea polyphenols (concentration over 6 g·L-1) showed certain irritation

hemolysis rates of other extracts were lower than 20%

so irritation was very light. Conclusion: Extracts from seven kinds of Chinese herbal medicine show certain anti-allergic properties. And within a predetermined addition amount

their irritating can be very light. So they might be used as allergy cosmetic additives.

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Related Institution

Jiangsu Province Second Hospital of Traditional Chinese Medicine

Nanjing University of Chinese Medicine

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