Sixty-two Cases of Essential Hypertension with Yin Deficiency and Yang Excess Treated by Supplementing Qingnao Jiangya Tablets

ZHU Mei; ZANG Yong-fa; MA Cai-hong

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Sixty-two Cases of Essential Hypertension with Yin Deficiency and Yang Excess Treated by Supplementing Qingnao Jiangya Tablets

更新时间：2024-01-04

- Sixty-two Cases of Essential Hypertension with Yin Deficiency and Yang Excess Treated by Supplementing Qingnao Jiangya Tablets
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 19, Issue 4, Pages: 292-294(2013)
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- Published：2013
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ZHU Mei, ZANG Yong-fa, MA Cai-hong. Sixty-two Cases of Essential Hypertension with Yin Deficiency and Yang Excess Treated by Supplementing Qingnao Jiangya Tablets[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(4): 292-294.
DOI：

ZHU Mei, ZANG Yong-fa, MA Cai-hong. Sixty-two Cases of Essential Hypertension with Yin Deficiency and Yang Excess Treated by Supplementing Qingnao Jiangya Tablets[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(4): 292-294. DOI：

摘要

目的: 观察加用清脑降压片治疗原发性高血压(阴虚阳亢)的临床疗效。方法: 124例原发性高血压患者随机分为治疗组和对照组各62例。两组均给予常规非药物治疗。对照组口服卡托普利25 mg/次

3次/d;治疗组加用清脑降压片

5片/次

3次/d。疗程8周。测定治疗前、4周及8周血压

检测治疗前后血清白介素6(IL-6)、白介素8(IL-8)和高敏C反应蛋白(hs-CRP)。结果: 治疗后第4周

8周治疗组SBP和DBP低于对照组(P<0.05

P<0.01);两组hs-CRP

IL-6

IL-8均较治疗前明显降低

治疗组低于对照组(PP结论: 清脑降压片治疗原发性高血压(阴虚阳亢)有较好的临床疗效

并能调节炎性因子

保护血管内皮。

Abstract

Objective: To observe the clinical effects of supplementing Qingnao Jiangya tablets for treatment of essential hypertension (yin deficiency and yang excess). Method: One hundred and twenty-four patients with essential hypertension were equally and randomly divided into treatment group and control group. Both two groups were given conventional non-drug therapy. The control group was given captopril orally 25 mg tid

and the treatment group was supplemented by Qingnao Jiangya tablets 5 tablets tid. Course of treatment were 8 weeks. Systolic and diastolic blood pressure (SBP

DBP) before treatment

4 weeks and 8 weeks after treatment were monitored. Inteleukin-6

8(IL-6

IL-8) and high-sensitivity C protein (hs-CRP) before and after treatment were detected. Result: SBP and DBP in treatment group at 4 weeks and 8 weeks after treatment were lower than those in the control group (P<0.05

P<0.01). IL-6

IL-8 and hs-CRP of both groups were lower than those before treatment

and the treatment group were lower than the control group (P<0.01). In the treatment group

the symptom curative effect and blood pressure control were better than those in the control group (P<0.01). Conclusion: The Qingnao Jiangya tablets have good clinical effects for treating essential hypertension (yin deficiency and yang excess type)

besides

it can also regulate the inflammatory factors

protect the vascular endothelium.

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