Effect of Asparagus Instant Powder on Sleep Improvement in Mice
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Effect of Asparagus Instant Powder on Sleep Improvement in Mice
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 23, Pages: 280-282(2012)
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Published:2012
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HUANG Yun-xiang, PENG You-shun, WANG Man, et al. Effect of Asparagus Instant Powder on Sleep Improvement in Mice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(23): 280-282.
DOI:
HUANG Yun-xiang, PENG You-shun, WANG Man, et al. Effect of Asparagus Instant Powder on Sleep Improvement in Mice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(23): 280-282.DOI:
Effect of Asparagus Instant Powder on Sleep Improvement in Mice
Objective: To study the effect of Asparagus instant powder (AIP) on sleep in mice. Method: Healthy KM male mice with the body weight of 18-22 g were divided into groups randomly. Then the mice were gavaged with AIP (containing 15% saponins) of low
middle and high doses (85
170
510 mg·kg-1); control group (water)and positive control (Jujuboside 360 mg·kg-1) respectively. The treatment was lasted for 30 days
the sleep-producing test was carried out by sub-threshold dose of sodium pentobarbital
and the incubation period test with sodium pentobarbital and the sleep extending test with sodium pentobarbital were also conducted. Result: AIP showed good sleep-producing action in sub-threshold dose test of sodium pentobarbital
could significantly shorten the incubation period induced by sodium pentobarbital
and could significantly prolong sleeping time induced by sodium pentobarbital. Conclusion: AIP can improve the sleep quality.