Objective:To study the effect and the mechanism of Feixin capsules on patients of chronic pulmonary heart disease (CPHD). Method: One hundred and twenty patients with CPHD were randomly divided into two groups. the control group and the treatment group

60 cases in each group. The control group was given the conventional therapy of western medicine alone. The treatment group was treated based on conventional therapy of western medicine and combined with Feixin capsules (4 capsules

tid). Before the treatment and two months after the treatment

typical symptoms

signs and complications were observed

and hemorheological parameters and blood gas analysis were examined. Result: The effective rates in the control group was 80% and 91.67% in the treatment group with significant difference (P<0.05). The results showed that the treatment group was better than the control group in improving and removing clinical symptoms and physical signs (P<0.01 or P<0.05). PaCO2 and PaO2 of the two groups were decreased and those after the treatment were increased

and the differences were statistically significant in the same group (P<0.01 or P<0.05). After treatment

the differences of PaCO2 and PaO2 were statistically significant between the two groups (P <0.05). The blood viscosity

plasma viscosity and hematocrit in two groups dropped after treatment

and the differences were statistically significant (P<0.01 or P<0.05). The differences of the blood viscosity

plasma viscosity and hematocrit were statistically significant between the two groups after treatment (P<0.05). Conclusion: The efficacy of Feixin capsules for treatment of CPHD is good

it is safe with less adverse reaction. It is worthy for popularizing clinical application.