Effect of Polysaccharides from Galli Gigerii Endothelium Corneum on Blood Lipid,Blood Glucose and Cellular Immune Function in Diabetes Mellitus Rats with Hyperlipidemia
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Effect of Polysaccharides from Galli Gigerii Endothelium Corneum on Blood Lipid,Blood Glucose and Cellular Immune Function in Diabetes Mellitus Rats with Hyperlipidemia
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 20, Pages: 255-258(2012)
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Published:2012
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JIANG Chang-xing, JIANG Din-yun, XIONG Qing-ping, et al. Effect of Polysaccharides from Galli Gigerii Endothelium Corneum on Blood Lipid,Blood Glucose and Cellular Immune Function in Diabetes Mellitus Rats with Hyperlipidemia[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 255-258.
DOI:
JIANG Chang-xing, JIANG Din-yun, XIONG Qing-ping, et al. Effect of Polysaccharides from Galli Gigerii Endothelium Corneum on Blood Lipid,Blood Glucose and Cellular Immune Function in Diabetes Mellitus Rats with Hyperlipidemia[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 255-258.DOI:
Effect of Polysaccharides from Galli Gigerii Endothelium Corneum on Blood Lipid,Blood Glucose and Cellular Immune Function in Diabetes Mellitus Rats with Hyperlipidemia
Objective:To study the effects of Polysaccharides from Galli Gigerii Endothelium Corneum (PECG) on blood lipid
blood glucose and immune function in diabetes mellitus rats with hyperlipidemia. Method: Wistar rats were feed with the high fat and sugar feedfor 30 d
thenthe rats was injected with streptozotocin intraperitoneally
continue to feed with high fat and sugar feed
meanwhile
administered orallywith 80
20 mg·kg-1 dosages of PECG for 40 d. Blood lipid
blood glucose and immune function in rats of different groups was observed.The index thymus and spleen were calculated. Result: The levels of total cholesterol (TC)
triaglyceride (TG)
low density lipoprotein cholesterol (LDL-C) and blood glucose decreased significantly (P<0.05) and those of high density lipoprotein cholesterol (HDL-C)
the index thymus and spleen increased greatly(P<0.05) and SI increased obviously in rats of high dose PECG group (P<0.05). Conclusion: PECG can decrease the level of fasting blood lipid and blood glucose in diabetes mellitus rats with hyperlipidemiaand improved cellular immune function significantly.