Optimization of Infiltration and Cutting Technology for Pieces of

LIANG Li-li; WANG Ying-zi; LI Huan-huan; SUN Xiu-mei

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Optimization of Infiltration and Cutting Technology for Pieces of

更新时间：2024-01-04

- Optimization of Infiltration and Cutting Technology for Pieces of
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 21, Pages: 28-30(2012)
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- Published：2012
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LIANG Li-li, WANG Ying-zi, LI Huan-huan, et al. Optimization of Infiltration and Cutting Technology for Pieces of [J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 28-30.
DOI：

LIANG Li-li, WANG Ying-zi, LI Huan-huan, et al. Optimization of Infiltration and Cutting Technology for Pieces of [J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 28-30. DOI：

摘要

目的: 优选板蓝根饮片的浸润切制工艺条件。方法: 以(R

S)-告依春、水浸出物、醇浸出物的含量为综合评价指标

选取药材浸润用水量、浸润时间、饮片厚度为考察因素

通过正交设计法优选板蓝根饮片的浸润切制工艺条件。采用质量法测定浸出物含量

HPLC测定(R

S)-告依春含量。结果: 影响板蓝根饮片浸润切制的主要因素为切片厚度

其次为浸润时间和浸润用水量。优选的板蓝根饮片的浸润切制工艺为板蓝根药材加0.6倍量水浸润20 h

切片厚度3 mm

60℃烘干。结论: 优选的浸润切制工艺稳定可行

为板蓝根饮片炮制工艺的规范化及质量标准提供实验依据。

Abstract

Objective: To optimize infiltration and cutting technology conditions for pieces of Isatis indigotica. Method: With the content of water extract

alcohol extract and (R

S)-goitrin as indexes

water consumption

infiltration time and thickness of pieces were selected as factors

infiltration and cutting technology for pieces of I. indigoticawas optimized by orthogonal test.The content of extract and (R

S)-goitrin were determined by gravimetric method and HPLC. Result: Thickness of pieces was major factor for infiltration and cutting technology of pieces of I. indigotica

followed by infiltration time and water consumption.Optimum infiltration and cutting technology was:infiltrated 20 h with 0.6 times the amount of pieces of I. indigotica

thickness of pieces 3 mm and drying at 60℃. Conclusion: Optimized infiltration and cutting technology was stable and feasible

it could provide experimental basis for processing technology standardization and quality standard of pieces of I. indigotica.

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Related Institution

College of Pharmacy，Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan & Education Ministry of P.R.China，The First Affiliated Hospital， Henan University of Chinese Medicine

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School of Pharmacy,Shihezi University

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