Optimization of Decoction Conditions of Compatibility of and Base on Dynamic Change of Chemical Components
|更新时间:2024-01-04
|
Optimization of Decoction Conditions of Compatibility of and Base on Dynamic Change of Chemical Components
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 24, Pages: 20-24(2012)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2012
稿件说明:
移动端阅览
QIN Su-hong, ZHANG Jin-ming, HE Yu-xin, et al. Optimization of Decoction Conditions of Compatibility of and Base on Dynamic Change of Chemical Components[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 20-24.
DOI:
QIN Su-hong, ZHANG Jin-ming, HE Yu-xin, et al. Optimization of Decoction Conditions of Compatibility of and Base on Dynamic Change of Chemical Components[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 20-24.DOI:
Optimization of Decoction Conditions of Compatibility of and Base on Dynamic Change of Chemical Components
Objective:To study on dynamic change rule of chemical components from Aconitum carmichaelii during decoction process after and before compatibility with Glycyrrhiza uralensis
in order to determine optimum decoction conditions of compatibility of G.uralensis and A. carmichaelii. Method: To determine optimum decoction conditions by determining the contents of total alkaloids and 3 kinds of double ester alkaloid in different decoction time
which were from single decoction liquid of A. carmichaelii and mixed decoction liquid of G.uralensis and A.carmichaelii.And rats cardiac toxicity of soup with optimum boiling technology was investigated. Result: Optimum boiling technology of G. uralensis-A. carmichaelii was:after boiling with a blaze
kept boiling 30 min with small fire.During 0-90 min decoction process
it showed different change trend of the contents of total alkaloids and 3 kinds of double ester alkaloid before and after compatibility of G. uralensis and A. carmichaelii
it reached to both comprehensive peak value in 30 min;both single decoction liquid of A. Carmichaelii and mixed decoction liquid of G. uralensis and A. carmichaelii showed some cardiac toxicity on rats in boiling 30 min
but cardiac toxicity of the latter was relative less. Conclusion: Optimized compatibility boiling technology could provide reference for 'reducing toxicity and storing efficacy’of A. carmichaelii in clinical application and traditional Chinese medicine compound.
Analysis on Dynamic Change of Stir-fried Glycyrrhizae Radix et Rhizoma Quality Based on "Exterior-interior Correlation"
Analysis of Flavonoid Content and Key Gene Expressions in Sprout and Seedling of Tartary Buckwheat
Effect of on Metabolism and Distribution and Excretion of Triptonide by LC-MS-MS
Related Author
XU Yue
JIA Zhe
WANG Yun
LI Bing
WU Deling
ZHANG Cun
Guang-tao QIAN
Er-kun CHAO
Related Institution
School of Pharmacy,Anhui University of Chinese Medicine
Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
Key Laboratory of Resource Plant Biology of Anhui Province,School of Life Sciences, Huaibei Normal University
Beijing Key Laboratory for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences