Objective: To establish the quality standard of Huazhi tablets. Method: Sophorae Flos

Aurantii Fructus

Rubiae Radix et Rhizoma

Notoginseng Radix et Rhizoma were identified by TLC. Rutin in Sophorae Flos was determined by HPLC. The separation was applied on a Fuji silysia C18 column(4.6 mm×150 mm

5 μm) with actetonitrile-0.2% phorsphoric acid as wobile phase; the flow rate was 1.0 mL·min-1

and detected at 256 μm. Result: Rutin

hesperidin

naringin

mollugin

ginsenoside Rg1 could be detected with clear spots and good separation by TLC. Rutin showed a good linear relationship in a range of 0.198-0.990 μg

r=1.000.The average recovery was 98.5% and RSD was 0.85%. Conclusion: The methods are available with a good reproducibility and can be used for the quality control of Huazhi tablets.