Investigation of Synchronous Release of Gastrodin and Turpentine Alcohot-biglucosid from Tianma Gouteng Decoction Oral Sustained Release Tablet
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Investigation of Synchronous Release of Gastrodin and Turpentine Alcohot-biglucosid from Tianma Gouteng Decoction Oral Sustained Release Tablet
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 23, Pages: 46-48(2012)
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Published:2012
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LIU Wen, SI Na, YANG Song, et al. Investigation of Synchronous Release of Gastrodin and Turpentine Alcohot-biglucosid from Tianma Gouteng Decoction Oral Sustained Release Tablet[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(23): 46-48.
DOI:
LIU Wen, SI Na, YANG Song, et al. Investigation of Synchronous Release of Gastrodin and Turpentine Alcohot-biglucosid from Tianma Gouteng Decoction Oral Sustained Release Tablet[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(23): 46-48.DOI:
Investigation of Synchronous Release of Gastrodin and Turpentine Alcohot-biglucosid from Tianma Gouteng Decoction Oral Sustained Release Tablet
采用相似因子进行释放曲线相似性比较。 结果: 天麻钩藤饮口服缓释片中天麻素和松脂醇二葡萄糖苷在体外可持续释放12 h
且具有同步性。 结论: 天麻钩藤饮缓释片具有同步缓释的溶出特点
天麻素和松脂醇二葡萄糖苷的释放具有相似性。
Abstract
Objective: To study on synchronous release of gastrodin and turpentine alcohot-biglucosid from Tianma Gouteng decoction sustained release tablet
and provide experimental basis for formulation reform of Tianma Gouteng decoction. Method: In vitro dissolution was investigated by rotating basket method
the content of gastrodin and turpentine alcohot-biglucosid were determined by HPLC
similar factor was adopted for comparing similarity of drug release curve by calculating cumulative dissolution ratio of medicinal components. Result: Gastrodin and turpentine alcohot-biglucosid could suatained relese 12 h in vitro
and had synchronization. Conclusion: Tianma Gouteng decoction sustained release tablet had dissolution characteristics of sustained release
release of gastrodin and turpentine alcohot-biglucosid had similarity.
Comparison of in Vitro Dissolution of Active Ingredients in Gastrodiae Rhizoma Powder with Different Particle Size
Study on Qualitative and Quantitative Methods of Fufangtianma Capsule
Study on the Composing Rule of Soup of Banxia, Baishu and Tianma
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Fan LIU
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Related Institution
Anhui Province Key Laboratory of Traditional Chinese Medicine,School of Pharmacy, Anhui University of Chinese Medicine
State Key Laboratory of Efficacy and Utilization of Medicinal Plants,Guizhou Medical University
Provincial Key Laboratory of Pharmaceutics in Guizhou Province, State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for Development and Application of Ethnic Medicine and Traditional Chinese Medicine, Ministry of Education, School of Pharmaceutical Sciences, Guizhou Medical University
The Affiliated Hospital of Guizhou Medical University