Therapeutic Mechanism of Total Organic Acid of Bunge on Experimental Primary Dysmenorrhea
|更新时间:2024-01-04
|
Therapeutic Mechanism of Total Organic Acid of Bunge on Experimental Primary Dysmenorrhea
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 21, Pages: 193-196(2012)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2012
稿件说明:
移动端阅览
ZHAO Pan, TONG Ji-ming, LIU Yu-ling, et al. Therapeutic Mechanism of Total Organic Acid of Bunge on Experimental Primary Dysmenorrhea[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 193-196.
DOI:
ZHAO Pan, TONG Ji-ming, LIU Yu-ling, et al. Therapeutic Mechanism of Total Organic Acid of Bunge on Experimental Primary Dysmenorrhea[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 193-196.DOI:
Therapeutic Mechanism of Total Organic Acid of Bunge on Experimental Primary Dysmenorrhea
Objective: To explore the therapeutic mechanism of the total organic acid of Thladiantha dubia Bunge(FTDBP) on the primary dysmenorrhea. Method: The primary dysmenorrhea model was induced by oxytocin in rat.The content of prostaglandin F2α(PGF2α) and endothelin(ET) were detected by Elisa assay
and the Ca2+ were detected by Methyl thymol blue(MTB). Result: Compare with model group
the content of PGF2α both in rat serum and uterus tissue decreased obviously by the FTDBP.And the content of ET and Ca2+ in uterus tissue were also significantly decreased compared to model group. Conclusion: Therapeutic mechanism of FTDBP on experimental primary dysmenorrheal may be related to restraining release or synthesis of PGF2α