Influence of Mongolian Medicine Hari Gabur-10 Flavor Tablets on Gastric Secretion and Pepsin Activity in Rats and Gastrointestinal Motility in Mice
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Influence of Mongolian Medicine Hari Gabur-10 Flavor Tablets on Gastric Secretion and Pepsin Activity in Rats and Gastrointestinal Motility in Mice
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 18, Pages: 262-265(2012)
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Published:2012
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BAOLE Chao-lu, WULAN Tu-ya, NA Sheng-sang. Influence of Mongolian Medicine Hari Gabur-10 Flavor Tablets on Gastric Secretion and Pepsin Activity in Rats and Gastrointestinal Motility in Mice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 262-265.
DOI:
BAOLE Chao-lu, WULAN Tu-ya, NA Sheng-sang. Influence of Mongolian Medicine Hari Gabur-10 Flavor Tablets on Gastric Secretion and Pepsin Activity in Rats and Gastrointestinal Motility in Mice[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 262-265.DOI:
Influence of Mongolian Medicine Hari Gabur-10 Flavor Tablets on Gastric Secretion and Pepsin Activity in Rats and Gastrointestinal Motility in Mice
0.38 g ·kg-1)对大鼠胃液分泌、胃蛋白酶活性的影响;采用比色法、固体排空法测定哈日嘎布日-10味片高、中、低剂量组对小鼠胃排空、小肠推进的影响。 结果: 哈日嘎布日-10味片高、中剂量组对大鼠胃液量、胃总酸度和胃蛋白酶活性及小鼠胃排空率均有显著的促进作用(P<0.05);哈日嘎布日-10味片高剂量组对小鼠小肠推进率有显著的促进作用(P<0.05)。 结论: 蒙药哈日嘎布日-10味片具有良好的消食、助消化作用。
Abstract
Objective: The evaluate the efficacy of the Hari Gabur-10 flavor tablets on digest. Method: The impact of the tablets (1.52
0.76
0.38 g ·kg-1)on pepsin activity and gastric secretion in rats was investigated by titration method and protein glass capillary method. The influence of the tablets (three doses) on gastric emptiness and intestinal propulsion was evaluated in mice through colorimetry and intestinal propulsion method. Result: Hari Gabur-10 flavored tablets could significantly promote gastric juice secretion in rats
increase gastric total acidity and pepsin activity;and accelerate the gastric emptying rate(P<0.05). It showed a certain role in propulsion of small intestine(P<0.05). Conclusion: Mongolian medicine Hari Gabur-10 flavor tablets has the effect of promoting digestion.