Clinical Research of Shenxiong Glucose Injection Treating Vascular Dementia and Influence on AVP
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Clinical Research of Shenxiong Glucose Injection Treating Vascular Dementia and Influence on AVP
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 21, Pages: 306-310(2012)
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Published:2012
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HE Jin-bo, JIN Jie. Clinical Research of Shenxiong Glucose Injection Treating Vascular Dementia and Influence on AVP[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 306-310.
DOI:
HE Jin-bo, JIN Jie. Clinical Research of Shenxiong Glucose Injection Treating Vascular Dementia and Influence on AVP[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 306-310.DOI:
Clinical Research of Shenxiong Glucose Injection Treating Vascular Dementia and Influence on AVP
Objective: To evaluate the clinical effect of Shenxiong glucose injection on vascular dementia and arginine vasopressin(AVP). Method: We chose 60 cases hospitalized patients according to the selection criteria
and randomLy divided into the treatment group of 30 cases and control group of 30 cases. On the basis of cell diphosphate choline sodium injection
the treatment group was given Shenxiong Glucose injection 200 mL
once daily
the control group was give Shuxuening injection 20 mL
once daily. The course lasted for 28 days. patients’ MMSE
ADL
Chinese medicine symptom scores
hemorrheologic indices and AVP content were observed. Result: ① In MMSE
ADL
Chinese medicine symptom scores before and after treatment
there was significant differences (P<0.05) between two groups; ②In MMSE
ADL
Chinese medicine symptom scores after treatment of one day between the two groups there was no significant difference; ③the whole blood viscosity
plasma viscosity
the red cell aggregation index
fibrinogen after treatment showed significant difference (P<0.05)
suggesting two groups can both improve blood rheology; But action of Shengxiong glucose injection was better than Shuxuening in degrading fibrinogen.④In treatment group plasma AVP content onday 29 of treatment is higher significantly than before treatment(P<0.05)
and the control group has no obvious changes
indicating that the treatment group have an effect on AVP. Conclusion: Shenxiong glucose injection has a good effect on VD patient
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Related Institution
Hubei Shizhen Laboratory
Hubei Provincial Institute of TCM,Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in TCM
Hubei Provincial Hospital of Traditional Chinese Medicine(TCM)
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