Metabolites of Mangrove Endophytic Fungus SK7RN3G1 from South China Sea
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Metabolites of Mangrove Endophytic Fungus SK7RN3G1 from South China Sea
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 21, Pages: 95-98(2012)
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Published:2012
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YANG Jian-xiang, QIU Sheng-xiang, SHE Zhi-gang, et al. Metabolites of Mangrove Endophytic Fungus SK7RN3G1 from South China Sea[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 95-98.
DOI:
YANG Jian-xiang, QIU Sheng-xiang, SHE Zhi-gang, et al. Metabolites of Mangrove Endophytic Fungus SK7RN3G1 from South China Sea[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(21): 95-98.DOI:
Metabolites of Mangrove Endophytic Fungus SK7RN3G1 from South China Sea
Objective: To study on secondary metabolites of mangrove endophytic fungus No·SK7RN3G1 from the south china sea. Method: The compounds were isolated by column chromatography and identified on the basia of physic-chemical constants and spectral analysis. Result: Six metabolites were obtained and elucidated as 3
N9- methyl -1- methyl -β- carboline (6). In the preliminary bioassay
1 and 2 show inhibittory activity on the HepG2 cell line with IC50 values of 20μg/mL and 25μg/mL
respectively. According to the literatures
5 shows anti HIV activity with EC50 values of 10.7 μmol ·L-1
6 hasimportant physiological activity of anti HIV and anticancer. Conclusion: The six metabolites were obtained from endophytic fungus No·SK7RN3G1 for the first time.
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Related Institution
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