Pharmacodynamic Effect of Mayinglong Eye Cream in Rats

WU Chuan-hong; GAO Jian; LI Shao-jing; SU Pei-yu; ZHANG Ning; LI De-feng; CHEN Chang; ZHANG Zhi-bin; YANG Hong-jun

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Pharmacodynamic Effect of Mayinglong Eye Cream in Rats

更新时间：2024-01-04

- Pharmacodynamic Effect of Mayinglong Eye Cream in Rats
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 17, Pages: 202-204(2012)
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- Published：2012
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WU Chuan-hong, GAO Jian, LI Shao-jing, et al. Pharmacodynamic Effect of Mayinglong Eye Cream in Rats[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 202-204.
DOI：

WU Chuan-hong, GAO Jian, LI Shao-jing, et al. Pharmacodynamic Effect of Mayinglong Eye Cream in Rats[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 202-204. DOI：

摘要

目的: 探讨马应龙八宝眼霜对黑眼圈的改善作用。方法: 本实验通过SD大鼠右后足足跖注射角叉菜胶致足肿胀

外涂2%

0.5%马应龙八宝眼霜

观察不同时间足跖肿胀度及给药前后足跖质量差

评价其抗炎作用;使用激光散斑血流监测视频系统监测SD大鼠耳廓血流

观察大鼠耳廓涂抹马应龙八宝眼霜后对血流的影响。结果: 马应龙八宝眼霜具有一定的抗炎作用;并且具有不同程度的降低耳廓血流灌注量的作用。结论: 马应龙八宝眼霜通过抗炎、降低血流量的作用可能对黑眼圈具有一定的改善作用。

Abstract

Objective: To explore the effects of Mayinglong eye cream on infraorbital dark circles. Method: The right rear toes of SD-rats were hypodermic injected with carrageenan and then coated with Mayinglong eye cream in different quality percentage (2%

0.5%) to observe toe swell at different times and toe weight before and after drug administration. Anti-inflammatory effect of Mayinglong eye cream was evaluated. The blood flow of auricle of SD-rats was monitored by Peri Cam PSI system. The effect of Mayinglong eye cream on regional blood flow of auricle skin surface was observed. Result: Mayinglong eye cream showed effects of anti-inflammation and reduced regional blood flow. Conclusion: Mayinglong eye cream could improve infraorbital dark circles via the effect of reducing blood flow and anti-inflammation.

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Related Institution

The NATCM Third Grade Laboratory of TCM Preparations，Key Laboratory of Liver and Kidney Diseases （Ministry of Education）， Shanghai Key Laboratory of Traditional Chinese Clinical Medicine， Shuguang Hospital Affiliated to Shanghai University of TCM

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine （TCM）

Institute of Chinese Materia Medica， Shanghai University of TCM

College of Pharmaceutical Sciences， Zhejiang Chinese Medical University

Biosafety Laboratory，Institute of Chinese Materia Medica， China Academy of Chinese Medical Sciences

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