Objective: To evaluate the effectiveness and safety of Jiajian Banxia Xiexin decoction for ulcerative colitis (UC). Method: All randomized controlled trials (RCTs) and quasi-RCTs on Jiajian Banxia Xiexin decoction for UC were searched in the VIP

CNKI

CBM disc and Wan fang. The quality of RCTs meeting inclusion criteria was evaluated and the related data were extracted; meta-analyses were performed with RevMan 5.1 software

and then the GRADE system was used to rate the level of evidence and strength of recommendations. Result: A total of 8 trials were included in this study

including 736 cases. Meta-analyses showed that: total effective rate OR=3.87

95% CI (2.47

6.05)

and had a better security. Based on GRADE

the level of evidence was grade C

and the strength of recommendations was weak. Conclusion: The present evidences show that: Jiajian Banxia Xiexin decoction has a better efficacy and safety

but key outcome should be evaluated. For the low quality and potential publication bias of included study

large-scale

the studies of high-quality researches and with TCM features should be performed.