Investigation of Extraction and Purification Technology for Qionggui Shuluo Granule
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Investigation of Extraction and Purification Technology for Qionggui Shuluo Granule
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 18, Pages: 59-61(2012)
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Published:2012
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DONG De-yun, ZANG chen, JIN Ri-xian, et al. Investigation of Extraction and Purification Technology for Qionggui Shuluo Granule[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 59-61.
DOI:
DONG De-yun, ZANG chen, JIN Ri-xian, et al. Investigation of Extraction and Purification Technology for Qionggui Shuluo Granule[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 59-61.DOI:
Investigation of Extraction and Purification Technology for Qionggui Shuluo Granule
Objective: To optimize extraction and purification technology of Qionggui Shuloug granule. Method: With transfer rate of ferulic acid as index
water extraction technology of Qionggui Shuloug granule was optimized by orthogonal test
soaking time
extraction times
extraction time and the amount of water were selected as factors
the content of ferulic acid was determined by HPLC;With transfer rate and purity of ferulic acid as indexes
single-factor test was used to investigate alcohol precipitation technology. Result: Optimized extraction technology was:soaked 1 h with 15 times the amount of water
extracted 2 times with 1 h per time;alcohol precipitation technology was:alcohol precipitation to the concentration of ethanol 60%
the relative density of 1.08-1.14(60℃). Conclusion: This optimized technology was stable and feasible
it could provide experimental basis for industrial production of Qionggui Shuloug granule.
Investigation of Extraction and Purification Technology for Qionggui Shuluo Granule
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Related Author
DONG De-yun1
ZANG Chen2
JIN Ri-xian1
LIU Bao-hua1
WANG Jin-yu2
GUAN Yongmei
WAN Zhiyan
WANG Shuhui
Related Institution
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Experiment Drug Factory,China Academy of Chinese Medical Sciences
Laboratory Animal Science and Technology Center,Jiangxi University of Chinese Medicine
National Key Laboratory of Modern Chinese Medicine Creation of Classic Prescriptions
Jiangxi University of Chinese Medicine,Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education