Effect of Jiajian Bufei Decoction on Content of ET and NO in Blood Plasma of Rats Model which Have Chronic Obstructive Pulmonary Disease
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Effect of Jiajian Bufei Decoction on Content of ET and NO in Blood Plasma of Rats Model which Have Chronic Obstructive Pulmonary Disease
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 17, Pages: 254-256(2012)
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Published:2012
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LI Xun. Effect of Jiajian Bufei Decoction on Content of ET and NO in Blood Plasma of Rats Model which Have Chronic Obstructive Pulmonary Disease[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 254-256.
DOI:
LI Xun. Effect of Jiajian Bufei Decoction on Content of ET and NO in Blood Plasma of Rats Model which Have Chronic Obstructive Pulmonary Disease[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 254-256.DOI:
Effect of Jiajian Bufei Decoction on Content of ET and NO in Blood Plasma of Rats Model which Have Chronic Obstructive Pulmonary Disease
Objective: To observe the effect of Jiajian Bufei decoction on plasma endothelin(ET) and nitric oxide(NO) in rats which have chronic obstructive pulmonary disease(COPD) and traditional Chinese medicine(TCM) syndrome such as 'Lung deficiency'. Method: The rats were divided randomly into groups and were given the medicine. Blood was detected for the contents of plasma endothelin-1(ET) and nitric oxide(NO) and comparisons were made between the groups. Result: The NO level in the large dosage group was markedly higher than that in the pathology control group. ET level in all treatment groups were both markedly lower than that in the pathology control group. Conclusion: Jiajian Bufei decoction can raise the NO and reducing the content of ET in blood plasma. Jiajian Bufei decoction can regulate the balance of ET and NO