Optimization of Flash Type Extraction Technology for  and

WANG Yue; DU Shou-ying; DAI Jun-dong; LU Yang; WEI Chang-ling; LU Xian-jin; LI Ying; LI Hui-yun; ZHAO Jing-yi

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Optimization of Flash Type Extraction Technology for and

更新时间：2024-01-04

- Optimization of Flash Type Extraction Technology for and
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 17, Pages: 5-8(2012)
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- Published：2012
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WANG Yue, DU Shou-ying, DAI Jun-dong, et al. Optimization of Flash Type Extraction Technology for and [J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 5-8.
DOI：

WANG Yue, DU Shou-ying, DAI Jun-dong, et al. Optimization of Flash Type Extraction Technology for and [J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 5-8. DOI：

摘要

目的: 优选当归、川芎配伍提取工艺

比较川芎、当归单提和共提液中阿魏酸的含量变化。方法: 以阿魏酸为指标

HPLC测定阿魏酸含量

选取提取时间、提取电压、乙醇用量及乙醇体积分数为考察因素

采用正交试验设计优选当归-川芎配伍闪式提取工艺

并用该优选工艺分别提取当归和川芎

比较单提、共提液中阿魏酸含量变化

探讨当归-川芎配伍的增效机制。结果: 最佳提取工艺为20倍量65%乙醇于100 V电压下闪式提取1.5 min;当归-川芎共提液中阿魏酸的含量与单提液之和相近。结论: 该优选工艺简单、经济

证实了当归、川芎配伍药理作用增强的原因并非阿魏酸含量的提高引起。

Abstract

Objective: To optimize compatibility extraction technology of Ligusticum chunxiong and Angelica sinensis

and compare the content of ferulic acid in Chinese herbal compound contain L. chunxiong and A. sinensis pair compatibility and single one. Method: With the content of ferulic acid as index which was determined by HPLC

compatibility extraction technology of L. chunxiong and A. sinensis was optimized by orthogonal test design with extraction time

extraction voltage

ethanol consumption and ethanol volume fraction as factors

and optimized process was used to extract L. chunxiong and A. sinensis single

the content variation of ferulic acid were compared in compatibility and single extraction

in order to investigate synergism mechanism of compatibility of L. chunxiong and A. sinensis. Result: Optimum extraction technology was:extracted 1.5 min with 20 times the amount of 65% ethanol

extraction voltage 100 V;The content of ferulic acid in compatibility extraction liquid was similar with the total content in single extraction liquid. Conclusion: This optimized technology was simple and economic

it confirmed that reason for enhancing pharmacological effect of compatibility with L. chunxiong and A. sinensis wasn't because of increasing the content of ferulic acid.

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Related Institution

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