Objective: To observe the impact about moxa flavone on animal experimental acne and pathology links. Method: To observe the influences of 60

30 mg·kg-1 moxa flavone on models of experimental rabbit ear keratinization

the influences of 60

30

15 mg·kg-1 moxa flavone on the models of the rat voix pedis engorgement and rats blood stasis syndrome. The influences of 100

50

25 mg·kg-1 moxa flavone on the models of the mice ear engorgement and the delayed hypersensitivity were evaluated. The treatment of moxa flavone on acne was evaluated. Result: 60 mg·kg-1 of moxa flavone can significantly reduce the level of ear keratinization of rabbit models and restrain obviously voix pedis engorgement of the rat models after 5 h medication(P<0.01);60 mg·kg-1 of moxa flavone has obviously improved the blood viscosity of rat acute in blood stasis model(P<0.01 and P<0.05); 100 mg·kg-1 of moxa flavone can significantly depress the ear engorgement of the mouse models (P<0.05) and the increasing CD4+ and CD8+ caused by the delayed hypersensitivity

and inhibit obviously the indexes of immune organs(P<0.05). Conclusion: The experiments show that moxa flavone can cure acne through the experimental keratinization

the blood circulation activating

stasis eliminating

antiinflammatory action

immunosuppression and androgen depreciation.