To summarize chlorogenic acid in absorption site and mechanism

metabolic site and pathways

and effect on pharmcokinetic parameters of chlorogenic acid with crude drugs compatibility.Recent relevant information and references were summarized

and further analyzed and reviewed.The current study showed that chlorogenic acid could be absorbed in the stomach

small intestine and large intestine

which was absorbed into the bloodstream in the original form by the stomach and small intestine.In addition

the absorption of chlorogenic acid was also affected by fasting or satiety.The main metabolic part of chlorogenic acid was in the intestine

as well as some in the liver.Chinese compatibility can promote the absorption and distribution of chlorogenic acid in the body in order to quickly reach peak concentration.We should carry out further studies on the main absorption site

mechanism of absorption in the stomach

the role of the metabolites of chlorogenic acid on its activity

and provide useful references to understand the process of chlorogenic acid in vivo

explore the association between absorption and metabolism with activity

and study pharmacokinetic.