Optimization of Extraction Technology for Volatile Oil from Shentong Zhuyu Decoction by Central Composite Design and Response Surface Methodology

RUAN Hong-sheng; MA Ding; LIU Shu-min

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Optimization of Extraction Technology for Volatile Oil from Shentong Zhuyu Decoction by Central Composite Design and Response Surface Methodology

更新时间：2024-01-04

- Optimization of Extraction Technology for Volatile Oil from Shentong Zhuyu Decoction by Central Composite Design and Response Surface Methodology
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 10, Pages: 60-63(2012)
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- Published：2012
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RUAN Hong-sheng, MA Ding, LIU Shu-min. Optimization of Extraction Technology for Volatile Oil from Shentong Zhuyu Decoction by Central Composite Design and Response Surface Methodology[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(10): 60-63.
DOI：

RUAN Hong-sheng, MA Ding, LIU Shu-min. Optimization of Extraction Technology for Volatile Oil from Shentong Zhuyu Decoction by Central Composite Design and Response Surface Methodology[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(10): 60-63. DOI：

摘要

目的: 优选身痛逐瘀汤中挥发油的提取工艺。方法: 以微波功率、料液比、提取时间为自变量

挥发油得率为因变量

通过对自变量各水平的多元线性回归及二项式拟合

采用星点设计-响应面法选取最佳工艺

并进行预测分析。结果: 最佳提取工艺条件为微波功率266.77 W

料液比1∶7.29

提取时间4.215 h

在此条件下

身痛逐瘀汤中挥发油提取得率的最大估计值为1.06%

试验结果与模型预测值相符。结论: 该方法简便合理

稳定

可预测性较好。

Abstract

Objective: To optimize extraction technology of volatile oil from Shentong Zhuyu decoction. Method: With microwave power

liquid-material ratio and extraction time as independent variables

yield of volatile oil as dependent variable

multiple linear regression and binomial of each level of independent variables were fitted. Optimum technology was selected by central composite design and response surface methodology

and prediction was carried out through comparing the observed and predicted values. Result: Optimum extraction technology parameters were as follows: microwave power 266.77 W

liquid-material ratio of 7.29∶1

extraction time 4.215 h. Under this conditions

maximum estimated value of volatile yield was 1.06% which was agreed with model predicted value. Conclusion: Optimized extraction technology was simple

reliable and high predictive.

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Related Author

RUAN Hong-sheng1

MA Ding1

LIU Shu-min1

YAO Xiao-yun

CHAO Qun-fang

CHEN Zhi-dan

YANG Bin-yin

WANG Gui-e

Related Institution

Research Institute of Traditional Chinese Medicine,Heilongjiang University of Traditional Chinese Medicine

Life Science and Technology College,Heilongjiang Bayi Agricultural University

College of Life Science and Technology,Xinjiang University

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

China Academy of Chinese Medical Sciences

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