Study on Effector Substance of Qingkailing Injection Directed by Meridian Distribution
|更新时间:2024-01-04
|
Study on Effector Substance of Qingkailing Injection Directed by Meridian Distribution
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 12, Pages: 139-142(2012)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2012
稿件说明:
移动端阅览
XIAO Lan, WANG Feng, ZHAO Xu-yuan. Study on Effector Substance of Qingkailing Injection Directed by Meridian Distribution[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(12): 139-142.
DOI:
XIAO Lan, WANG Feng, ZHAO Xu-yuan. Study on Effector Substance of Qingkailing Injection Directed by Meridian Distribution[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(12): 139-142.DOI:
Study on Effector Substance of Qingkailing Injection Directed by Meridian Distribution
Objective: Directed by meridian distribution of Radix Scutellariae
studying effector substance of Qingkailing injection. Method: Qingkailing injection was given to experimental rats
the brain
liver and lung were collected in various time. Then Qingkailing was injected to both normal and cerebral isehemia-reperfusion rats
the brain
liver and lung were collected at various time. The concentration of baicalin from samples was determined by HPLC-MS. Result: After iv Qingkailing injection
considerable baicalin was distributed quickly to target tissue of normal rats
ie liver and lung; the content of baicalin in the brain was minimum. In cerebral ischemia-reperfusion rats
the concentration of baicalin in the brain was higher than that of normal rats. Conclusion: Baicalin is one of effector substance of Qingkailing injection curing lung
liver and cerebral ischemia disease. It is feasibility to search for effector substance of complex prescription
directed by meridian distribution of traditional Chinese medicine.
Effect of Berberine-Baicalin Combination on Fecal Microbiota Transplantation-induced Type 2 Diabetes Mellitus Due to Internal Accumulation of Dampness-heat in Mice from Perspectives of Gut Microbiota and Metabolomics
Baicalin Induces Ferroptosis in Gastric Cancer Cells via p53-mediated SLC7A11 Down-regulation
Synergistic Effect of Xiangdan Injection and Qingkailing Injection on Organ Injury Caused by Acute Inflammation and Thrombosis in Rats
Investigation of Effect of Polyethylene Glycol 400 on Pharmacokinetics and Anti-inflammatory Effect of Baicalin Based on UPLC-MS/MS and Molecular Docking Techniques
Clinical Research of Qingkailing Injection in Adjuvant Treatment of Sepsis and Heat Syndrome in Children
Related Author
CHEN Mengjie
LIU Yimin
ZHOU Yun
YU Keming
XIA Min
LIU Hongning
JI Yanhua
ZENG Zhijun
Related Institution
Research Center for Differentiation and Development of Traditional Chinese Medicine (TCM) Basic Theory, Jiangxi Province Key Laboratory of TCM Etiopathogenisis, Jiangxi University of Chinese Medicine
Henan Academy of Chinese Medicine
The Second Clinical Medical College, Henan University of Chinese Medicine
Key Laboratory of Beijing for Identification and Safety of Chinese Medicine,State Key Laboratory of Innovative Natural Medicine and Traditional Chinese Medicine Injections,Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences
State Key Laboratory of Functions and Applications of Medicinal Plants,School of Pharmaceutical Sciences,Engineering Center of Microbiology and Biochemical Pharmacy,Experimental Animal Center,Guizhou Medical University