Optimization of Ultrasonic-assisted Extraction Technology for Total Flavonoids from  by Response Surface Methodology and Evaluation Its  Antioxidant Activity

XU Xiu-quan; YU Qian; XU Ying; XU Hui-min

您当前的位置：

首页 >

文章列表页 >

Optimization of Ultrasonic-assisted Extraction Technology for Total Flavonoids from by Response Surface Methodology and Evaluation Its Antioxidant Activity

更新时间：2024-09-23

- Optimization of Ultrasonic-assisted Extraction Technology for Total Flavonoids from by Response Surface Methodology and Evaluation Its Antioxidant Activity
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 18, Pages: 38-41(2012)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2012
- 稿件说明：
移动端阅览
XU Xiu-quan, YU Qian, XU Ying, et al. Optimization of Ultrasonic-assisted Extraction Technology for Total Flavonoids from by Response Surface Methodology and Evaluation Its Antioxidant Activity[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 38-41.
DOI：

XU Xiu-quan, YU Qian, XU Ying, et al. Optimization of Ultrasonic-assisted Extraction Technology for Total Flavonoids from by Response Surface Methodology and Evaluation Its Antioxidant Activity[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 38-41. DOI：

摘要

目的: 优化赶黄草总黄酮的超声提取工艺并分析其体外抗氧化活性。方法: 以总黄酮得率为指标

在单因素试验基础上

采用响应面设计法对影响总黄酮得率的乙醇体积分数、超声时间及料液比进行优化

同时考察其体外抗氧化活性。结果: 赶黄草总黄酮超声提取的最佳工艺条件为26倍量60%乙醇于50℃下超声提取20 min。在此条件下

总黄酮得率4.14%

试验结果与模型预测值相符。体外抗氧化活性研究表明

赶黄草总黄酮具有较强的还原力和总抗氧化能力

同时具有较强的清除羟基自由基和DPPH自由基能力。结论: 该优选工艺方便、快捷、高效;赶黄草总黄酮具有较强的抗氧化活性

值得深入研究。

Abstract

Objective: To optimize ultrasonic-assisted extraction technology of total flavonoids from Penthorum chinense and evaluate its in vitro antioxidant activity. Method: With yield of total flavonoids as index

the concentration of ethanol

extraction time

liquid-material ratio were optimized by response surface methodology based on single-factor tests

and its in vitro antioxidant activity were evaluated by multi-test systems. Result: Optimal extraction technology conditions were:extracted 20 min with 26 times the amount of 60% ethanol at 50℃. Under these conditions

yield of total flavonoids reached 4.14%

which was agreed with model predictions.In vitro antioxidant activities results showed that total flavonoids from P. chinense had good antioxidant activities of scavenging DPPH free radical and hydroxyl free radical

but also had strong reducing power and total antioxidant capability. Conclusion: Optimized ultrasonic-assisted extraction technology was simple

rapid and efficient.Total flavonoids from P. chinense had good antioxidant activity which was worth of further study.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Optimization of Ultrasonic-assisted Extraction Technology for Total Flavonoids from Penthorum chinense by Response Surface Methodology and Evaluation Its in vitro Antioxidant Activity

Application of CCD-RSM for Optimization of Total Flavonoids Extraction in

Optimization of Ultrasound-assisted Extraction of Total Flavonoids fromby Response Surface Methodology

Extraction Technology of Flavonoid in Mongolian Medicine and Its Antioxidative Activation

Related Author

XU Xiu-quan

YU Qian

XU Ying

XU Hui-min

XIE Zhen

CHEN Yong

ZENG Hai-sheng

WEI Tao

Related Institution

School of Pharmacy,Jiangsu University

Center for Physical and Chemical Analysis,Xinjiang University

Pharmacy Technology Center，Tsinghua University

Center of Pharmacy R&D，XinJiang Huachun Bio-Pharmaceutical Co. Ltd.

School of Life Sciences， Tsinghua University

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰