Optimization of Extraction Process for Based on Viability of Myocardial Cell
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Optimization of Extraction Process for Based on Viability of Myocardial Cell
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 18, Pages: 17-19(2012)
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Published:2012
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CAI Lin, MENG Xian-sheng, BAO Yong-rui, et al. Optimization of Extraction Process for Based on Viability of Myocardial Cell[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 17-19.
DOI:
CAI Lin, MENG Xian-sheng, BAO Yong-rui, et al. Optimization of Extraction Process for Based on Viability of Myocardial Cell[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 17-19.DOI:
Optimization of Extraction Process for Based on Viability of Myocardial Cell
Objective: To optimize extraction technology of Pueraria lobata. Method: With the content of puerarin and pharmacodynamics of in vitro myocardial cell viability as comprehensive analysis indexes
orthogonal test was used to optimize extraction technology with extraction time
solid-liquid ratio
extraction times and the concentration of ethanol as factors. Result: The best extract condition of P. lobata was:refluxing extracted 2 times with 6 times the amount of 70% ethanol
1.5 h per time. Conclusion: Combining with chemical and pharmacodynamic indexes to optimize extraction and purification process could better guarantee quality of preparations
and this optimized technology was stable and feasible.