Optimization of Extraction Technology for Dihydromyricetin from by Response Surface Analysis Methodology
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Optimization of Extraction Technology for Dihydromyricetin from by Response Surface Analysis Methodology
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 17, Pages: 46-49(2012)
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Published:2012
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XIE Yu-feng, CHEN Zhuo-han, LV Hua-chong. Optimization of Extraction Technology for Dihydromyricetin from by Response Surface Analysis Methodology[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 46-49.
DOI:
XIE Yu-feng, CHEN Zhuo-han, LV Hua-chong. Optimization of Extraction Technology for Dihydromyricetin from by Response Surface Analysis Methodology[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(17): 46-49.DOI:
Optimization of Extraction Technology for Dihydromyricetin from by Response Surface Analysis Methodology
Objective: To optimize extraction process of dihydromyricetin from Ampelopsis grossedentata by response surface methodology. Method: With extraction ratio of dihydromyricetin as index
based on single factor test
the concentration of ethanol
liquid-solid ratio and extraction time were selected as independent variables and extraction rate of dihydromyricetin as response value
response surface methodology with three-factors and three-levels was carried out for optimizing extraction process of dihydromyricetin from A. grossedentata. Result: Optimum extraction conditions of dihydromyricetin were as followed:refluxing extracted 95 min with 17 times the amount of 81% ethanol. Under these conditions
extraction ratio of dihydromyricetin was 9.58%
relative error in comparison with the predicted one was 0.14%. Conclusion: This optimized technology was reliable
it showed that was feasible for optimizing extraction technology of dihydromyricetin by response surface methodology.
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