Objective: To observe the clinical efficacy and safety of Yiqi Jianpi fang for treating the patients with colon cancer after surgical operation. Method: Sixty cases of patients with colon cancer after surgical operation were randomly divided into observation group and control group. The all patients underwent radical resection

two days after the observation group was given the treatment of Yiqi Jianpi fang

the control group was given only conventional western medicine.The clinical efficacy was evaluated in after one month of continuous treatment

the postoperative first exhaust and defecation time

the white blood cell(WBC) count were observed

th bowel function recovery time and adverse circumstances of the two groups were compared. Result: The effective rate of traditional Chinese medicine (TCM) syndrome score of observation group was 86.7%

the was control group 66.7%

the difference was significant between the two groups (P<0.01). The effective rate of kamofsky performance status(KPS) score of observation group was 90.0%

the control group was 70.0%

the difference was significant between the two groups(P<0.01). After treatment the WBC count of observation group was significantly lower than the control group

compared the difference was significant (P<0.05). The first exhaust and defecation time of observation group was significantly ahead of schedule

compared with the control group the difference was significant (P<0.05). The Ⅲ-Ⅳ adverse events incidence rate of observation group was 20.0%

the control group was 73.3%

the difference was significant between the two groups(P<0.01). Conclusion: The Yiqi Jianpi fang for treating the patients with colon cancer after surgical operation has better clinical efficacy

can promote postoperative recovery of bowel function

reduce the postoperative inflammatory response

and can reduce the incidence of adverse reaction and degree of occurrence. So it is safe and valuable as a treatment method for the colon cancer after surgical operation.