Screening the Effective Parts from Erchen Decoction for Expectorant and Antitussive
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Screening the Effective Parts from Erchen Decoction for Expectorant and Antitussive
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 12, Pages: 218-221(2012)
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Published:2012
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ZHANG Chao-yun, ZHANG Xiao-fen, ZHANG Xue-peng, et al. Screening the Effective Parts from Erchen Decoction for Expectorant and Antitussive[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(12): 218-221.
DOI:
ZHANG Chao-yun, ZHANG Xiao-fen, ZHANG Xue-peng, et al. Screening the Effective Parts from Erchen Decoction for Expectorant and Antitussive[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(12): 218-221.DOI:
Screening the Effective Parts from Erchen Decoction for Expectorant and Antitussive
Objective: To screen the effective parts from Erchen Tang for expectorant and antitussive. Method: The mice were allotted into 12 groups as following: physiogical saline
DHS group
the five part from Erchen decocotion groups with high dose(HD) and low dose(LD
15
3.75 g·kg-1)
the mice were orally administered for 3 days
the antitussive effect was observed by concentrated ammonia method after 1 h. The mice were allotted into 12 groups as following: physiogical saline
AHOS group
the five part fron Erchen decocotion groups with high dose(HD) and low dose(LD
15
3.75 g·kg-1)
the mice were orally administered for 3 days
the expectorant effect was observed by increased the secretion of expect oration method after 30 min. The cavies were allotted into 12 groups as following: physiogical saline aminophylline group
the five part from Erchen decoction groups with high dose(HD) and low dose(LD
8.32
2.08 g·kg-1)
the cavies were orally administered for 3 days
the antiasthmatic effect was observed by spray method after 1 h. Result: Essential oil
butanol and water fractions could reduce the frequency of cough
and increase secretion of expectoration
and inhibitory asthma(P<0.01
P<0.05);petroleum ether and ethyl acetate fractions could not reduce the frequency of cough
could not increase secretion of expectoration
and inhibitory asthma. Conclusion: The results show that petroleum ether and ethyl acetate fractions were invalid
essential oil
butanol and water fractions were the effective parts of Erchen Tang for expectorant and antitussive.
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Related Author
LI Jiangtao
XU Dan
LI Zheng
WANG Ling
LI Fengsen
LI Xiangpeng
Hao WU
Xiao-yin WEN
Related Institution
Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine
The Fourth Clinical Medical College of Xinjiang Medical University
National Clinical Research Center for Respiratory Disease,State Key Laboratory of Respiratory Disease,Guangzhou Institute of Respiratory Health,The First Affiliated Hospital of Guangzhou Medical University
Guangdong Institute of Nanshan Pharmaceutical Innovation
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