Objective:To assess the efficacy of modified Dachengqi decoction in treatment of severe acute pancreatitis(SAP). Method:We searched Chinese database on line by computer and chose articles according to the inclusive and exclusive standards. Then we evaluated the quality of the included articles strictly and obtain information. A Meta analysis was performed using RevMan 4.2.2 software to contrast the disappearing time of abdominal pain

recovering time of serum amylase

clinical efficacy and the hospital period. Result:Twelve clinical articles including 621 cases were analyzed.Compared with conventional treatment group

we detected significant differences between two group in disappearing time of abdominal pain [SMD=-1.75

95%CI(-2.10

-1.41)

P<0.000 01]

recovering time of serum amylase [SMD=-2.00

95%CI(-2.73

-1.27)

P<0.000 01]

clinical efficacy[OR=3.78

95%CI(2.27

6.28)

P<0.000 01]

hospitalperiod[SMD =-1.51

95%CI(-1.99

-1.03)

P<0.000 01]. Conclusion:Modified Dachengqi decoction can significantly shorten the time of abdominal pain and the course of severe acute pancreatitis

and enhance clinical efficacy.