Comparative Study on Cooling Blood between Radix Paeoniae Rubra and Radix Paeoniae Alba(Ⅱ)——Spectrum-effect Analysis on Inhibitory Apoptosis of LPS-stimulated Rat Alveolar Macrophages
|更新时间:2024-01-04
|
Comparative Study on Cooling Blood between Radix Paeoniae Rubra and Radix Paeoniae Alba(Ⅱ)——Spectrum-effect Analysis on Inhibitory Apoptosis of LPS-stimulated Rat Alveolar Macrophages
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 6, Pages: 181-184(2012)
作者机构:
作者简介:
基金信息:
DOI:
CLC:
Published:2012
稿件说明:
移动端阅览
SONG Yu-chao, CUI Xiu-rong, LIAN Chao-jie, et al. Comparative Study on Cooling Blood between Radix Paeoniae Rubra and Radix Paeoniae Alba(Ⅱ)——Spectrum-effect Analysis on Inhibitory Apoptosis of LPS-stimulated Rat Alveolar Macrophages[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(6): 181-184.
DOI:
SONG Yu-chao, CUI Xiu-rong, LIAN Chao-jie, et al. Comparative Study on Cooling Blood between Radix Paeoniae Rubra and Radix Paeoniae Alba(Ⅱ)——Spectrum-effect Analysis on Inhibitory Apoptosis of LPS-stimulated Rat Alveolar Macrophages[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(6): 181-184.DOI:
Comparative Study on Cooling Blood between Radix Paeoniae Rubra and Radix Paeoniae Alba(Ⅱ)——Spectrum-effect Analysis on Inhibitory Apoptosis of LPS-stimulated Rat Alveolar Macrophages
Objective: To study the fingerprints correlated with pharmacological effect on the basis of LC-MS fingerprint and data of Radix Paeoniae Alba and Radix Paeoniae Rubra
in order to definite the effective compounds of decreasing apoptosis induced by lipopolysaccharide in the alveolar macrophages. Method: The inherent connections were studied between LC-MS fingerprint and decreasing apoptosis of Radix Paeoniae Alba and Radix Paeoniae Rubra
which was induced by lipopolysaccharide in the alveolar macrophages
with partial least squares regression (PLSR). Result: Effective compounds consist of five peaks X8
X10
X3
X7
X13of the fingerprint play the most important role in the decreasing apoptosis induced by lipopolysaccharide in the alveolar macrophages. Conclusion: The 'effective compounds’are the key of quality evaluation of traditional Chinese medicine and can provide comparatively comprehensive information of Chinese medicine.
A Comparison on Pharmacological Actions Between Radix Paeoniae Rubra and Radix Paeoniae Alba
Mechanism of Radix Paeoniae Rubra-Radix Aconiti Lateralis in Treatment of Acute-on-chronic Liver Failure Based on Macrophage Polarization
Experimental study of compatible application of RHIZOMA CHUANXIONG and RADIX PAEONIAE RUBRA on regulation of lipid metabolism, scavenging of free radicals and protcction of vascular endothelium in hyperlipidemia rat
Adsorption and Separation Properties of D Resin for Purification of Paeoniflorin
Study on Quality Standards for Jiangu Juantong Capsules
Related Author
WANG Zheng-tao
HU Yue-juan
LI Ying-wei
LU Lan
WANG Rui
Yunan CAO
Chenqin TANG
Jie PENG
Related Institution
Hunan University of Chinese Medicine
The First Affiliated Hospital of Hunan University of Chinese Medicine
Chengdu University of Traditional Chinese Medicine,The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicines,The Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Constructioned by The Ministry of Science and Technology of the PRC and Sichuan Province