Objective: To observe the therapeutic effects of Toutongning capsule in the treatment of patients with migraine and its effects on blood platelet and hemorrheological paramters. Method: Three hundredend thirty-sixty patients with migraine were divided randomly into two groups: Toutongning treatment group (treatment group)168 cases (giving Toutongning capsule

3 capsules each time

3 times a day)

Xibiling treatment group(contral group) 168 cases(giving Xibiling capsule

one capsule each time

2 times a day).A treatment course is composed of 2 weeks. The therapeutic effects and the changes of blood platelet and hemorrheological paramters were observed in two group. Result: The total effective rates of the treatment group and the contral group were 89.9% and 72.6%

respectively(P<0.05).The changes of blood platelet and hemorrheological paramters were significantly higher after teratment than those before teratment in teratment group(P<0.05 or P<0.01). Conclusion: Toutongning capsule can restrain the blood platelet gather

decrease whole blood viscosity

improve the blood circulation

and which is safe and effective in treating Patients with Migraine.