Investigate on Hygroscopicity of Carbohydrate Composition from Yiganning Aqueous Extract

GUI Hui; YAN Hang; LI Jing; XIA Xin-hua

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Investigate on Hygroscopicity of Carbohydrate Composition from Yiganning Aqueous Extract

更新时间：2024-01-04

- Investigate on Hygroscopicity of Carbohydrate Composition from Yiganning Aqueous Extract
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 14, Pages: 32-35(2012)
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- Published：2012
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GUI Hui, YAN Hang, LI Jing, et al. Investigate on Hygroscopicity of Carbohydrate Composition from Yiganning Aqueous Extract[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(14): 32-35.
DOI：

GUI Hui, YAN Hang, LI Jing, et al. Investigate on Hygroscopicity of Carbohydrate Composition from Yiganning Aqueous Extract[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(14): 32-35. DOI：

摘要

目的: 探讨乙肝宁中糖类成分的吸湿性。方法: 以乙肝宁为模型药物

采用不同分离纯化方法得到总多糖、总单糖、总低聚糖成分

干燥

粉碎

测定吸湿百分率及临界相对湿度。运用HPLC-ELSD测定糖类组成。结果: 乙肝宁浸膏临界相对湿度为67.3%

总多糖、总单糖、总低聚糖的临界相对湿度分别为78.4%

62.2%

68.3%。总单糖中主要含果糖

低聚糖中小分子糖主要为果糖

葡萄糖

蔗糖。结论: 糖类是乙肝宁吸湿性增大的因素之一

其中果糖吸湿性最大。

Abstract

Objective: To investigate hygroscopicity of carbohydrate composition in Yiganning aqueous extract. Method: With Yiganning grain as a model drug

total polysaccharides

total monosaccharides and total oligosaccharides were obtained by different separation and purifycation method

and then drying

crushing

hygroscopic percentage and critical relative humidity(CRH) were determined.HPLC-ELSD was used to detect carbohydrate composition by gradient elution method. Result: CRH of Yiganning extract was 67.3%

CRH of total polysaccharide

total monosaccharides and total oligosaccharides were 78.4%

62.2%

68.3%

respectively.Main components of total monosaccharides was fructose

small molecules carbohydrate in oligosaccharides was fructose

glucose and sucrose. Conclusion: Carbohydrate components was one factor of increasing hygroscopicity in Yiganning dry extract

hygroscopicity of fructose was largest.

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Related Author

WANG Zhenxing

FAN Mengmeng

NIU Le

CAO Suqin

LI Hongwei

ZHANG Zhenling

LI Hanwei

ZHU Jianguang

Related Institution

Henan Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yuyao，Henan Research Center for Special Processing Technology of Chinese Medicine，Henan University of Chinese Medicine

National & Local United Engineering Laboratory for TCM Advanced Manufacturing Technology, Tasly Pharmaceutical Co. Ltd.

School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine (TCM)

Kangmei Pharmaceutical Co.Ltd.

School of Pharmaceutical Sciences, Peking University

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