Preparation Technology of Total Saponins from Combined with Icariin Chitosan Microspheres
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Preparation Technology of Total Saponins from Combined with Icariin Chitosan Microspheres
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 5, Pages: 30-33(2012)
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Published:2012
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SU Ming, LI Na, TIAN Jing-zhen. Preparation Technology of Total Saponins from Combined with Icariin Chitosan Microspheres[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(5): 30-33.
DOI:
SU Ming, LI Na, TIAN Jing-zhen. Preparation Technology of Total Saponins from Combined with Icariin Chitosan Microspheres[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(5): 30-33.DOI:
Preparation Technology of Total Saponins from Combined with Icariin Chitosan Microspheres
Objective: To prepare total saponins of Panax notoginseng combined with icariin chitosan microspheres(PNS-ICA-CS-MS)and study influence of preparation technology parameters on drug encapsulation efficiency of PNS-ICA-CS-MS. Method: PNS-ICA-CS-MS was prepared by emulsion crosslinking method with chitosan as carrier.Based on result of single factor test
optimum preparation technology was optimized by orthogonal design method with drug loading and encapsulation efficiency as indexes. Result: Optimum preparation technology conditions were the concentration of emulsifier 4 %
the concentration of chitosan 4 %
proportion of oil-water 8∶1 and stirring speed 400 r·min-1. Conclusion: PNS-ICA-CS-MS were good shape and high encapsulation rate and its technology was stable.
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