To make the analysis of literature about flavescens and its active ingredient in the treatment of insomnia. Search terms were flavescens

matrine

oxymatrine

insomnia. The full text journal database (CNKI) literature of the past ten years were retrieved

and then to select and reference literature from the pathology and treatment of insomnia medication

as well as the sophora flavescens and its active ingredients mechanism.Forty literatures were quoted among four hundred and fifty-two items. Material basis and the homeostatic regulation of sleep imbalances are the main pathological cause of insomnia. Flavescens and its active ingredients can increase the brain of a sedative neurotransmitters

and then perform the effect on insomnia. Flavescens and its active ingredient could pass through the blood-brain barrier

regulate neurotransmitters in the brain and result in central sedation

and then to perform the effect on insomnia. In further studies

flavescens and its related agents should be developed and application.