Optimization of Extraction Technology for Baoxin Dripping Pill

CHEN Chao; ZHOU Fu-jun; HAN Zhong-yao; ZHU Xiao-wei; HOU Wen-bin

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Optimization of Extraction Technology for Baoxin Dripping Pill

更新时间：2024-01-04

- Optimization of Extraction Technology for Baoxin Dripping Pill
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 10, Pages: 69-71(2012)
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- Published：2012
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CHEN Chao, ZHOU Fu-jun, HAN Zhong-yao, et al. Optimization of Extraction Technology for Baoxin Dripping Pill[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(10): 69-71.
DOI：

CHEN Chao, ZHOU Fu-jun, HAN Zhong-yao, et al. Optimization of Extraction Technology for Baoxin Dripping Pill[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(10): 69-71. DOI：

摘要

目的: 优选保心滴丸的提取工艺。方法: 以丹酚酸B为检测指标

采用正交试验优选丹参和山楂的乙醇回流提取工艺;以阿魏酸和二苯乙烯苷为检测指标

采用正交试验优选处方中三七等其余药材的乙醇渗漉提取工艺。结果: 保心滴丸最佳提取工艺为丹参、山楂加6倍量70％乙醇提取3次

每次1 h;三七、首乌、制首乌、川芎采用渗漉提取

10倍量60%乙醇浸泡18 h

滴速10 mL·min-1·kg-1。结果: 优选的保心滴丸提取工艺稳定可行

可推广于工业化生产。

Abstract

Objective: To optimize extraction process of Baoxin dripping pill. Method: Ethanol extraction technology of Crataegus pinnatifida and Salvia miltiorrhiza was optimized by orthogonal test with salvianolic acid B as detection index.With the content of ferulic acid and stilbene glucoside as index

orthogonal test was used to optimize percolation process of Panax notoginseng and other herbs from Baoxin dripping pill. Result: Optimum extraction process conditions were determined as follows:C. pinnatifida and S. miltiorrhiza was extracted 3 times with 6 times the amount of 70% ethanol

1 h each time.P. notoginseng and other herbs were extracted by percolation technology

these herbs were soaked 18 h with 10 times the amount of 60% ethanol

dripping rate 10 mL·min-1. Conclusion: This optimized extraction technology of Baoxin dripping pill was stable and feasible

it could be extended to industrial production.

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