Objective: To study the effectd of Cistanche Herba on swimming ablity antioxidant resistance of. mitochondrial in rats Method: One hundred and twenty male Wistar rats were randomly divided into static ig water group (C group)

still ig Cistancht Herba group(M group)

exercise ig water group (T group)

group exercise ig Cistanches Herba 1-4 (TM 1-4 group). A professional device ig 1 times a day. TM 1-4 ig dose group were 6.01

9.97

13.94

17.90 g·kg-1

ig volume 5 mL·kg-1

C

T two groups ig distilled water. 4 weeks after exhaustive swimming training

measured body weight

swimming time and heart mitochondria in malondialchehy-che(MDA)

superoxide dismutase(SOD)

glutathione peroxidase(GSH-Px) levels and other indicators related with fatigue. Result: TM weight of each group is greater than the T group (P<0.05)

swimming time longer than T group (P<0.01)

TM each group no significant differences. Result of exhaustive swimming in the MDA content in rat heart mitochondria was significantly increased

T-group and TM 1-4 group were increased to (5.96±0.71)

(5.05±0.36)

(5.05±0.92)

(5.06±0.16)

(5.05 ±0.25) μmol·L-1

and that the TM groups were significantly different lower than the T group (P<0.01); SOD

GSH-Px activity was significantly decreased (T-group and T1-T4 group

SOD decreased to (209.78±17.21)

(249.85±10.93)

(253.98±9.64)

(259.31±14.57)

(259.46±15.73) U·mL-1

GSH-Px decreased to (57.95±11.95)

(68.58±6.01)

(70.63±5.83)

(70.78±7.04)

(72.56±4.34) U·mg-1

and that the TM groups were significantly higher than the T group (P<0.01); TM of each group showed no significant difference. Conclusion: Cistanches Herba has improved exercise capacity in rat heart mitochondria and the role of antioxidant enzymes

there by reducing free radicals on myocardial sarcoplasmic reticulum and mitochondrial membrane damage

inhibition of high-intensity exhaustive exercise cause myocardial mitochondrial oxidative damage

delay fatigue occurred; have a significant effect at a dose of 6.01 g·kg-1.