Objective : To investigate the applicability of the detection of bacterial endotoxin in five kinds of traditional Chinese medicine injections by nonspecific and specific tachypleus amebocyte lysate(TAL) of kinetic turbidimetric assay. Method: Yuxingcao

Shuanghuanglian

Qingkailing

Gegensu

and Xiangdan injections were detected by nonspecific and specific TAL lysate of kinetic turbidimetric assay. Result: There were less interferences during detective process of achromaticity injections such as Yuxingcao and Gegensu

on the other hand

there were more interference of multi-component and dark color such as Shuanghuanglian

Qingkailing

and Xiangdan injections using TAL of kinetic turbidimetric assay

interference was big and the result was instable. The interference could be removed effectively by using specific TAL of kinetic turbidimetric assay

such as the case of Qingkailing. However

the interference for shuanghuanglian

Xiangdan injections could not be eliminated interference using this method. Conclusion : It is feasible to perform the bacterial endotoxin test on Yuxingcao and Gegensu injection using normal TAL and specific TAL through kinetic turbidimetric assay

using specific TAL of kinetic turbidimetric assay as a substitute for nonspecific is a effective method in removing the interference for Qingkailing injection

the detection result of Shuanghuanglian and Xiangdan injection are instable.