Clinical Significance of Detecting Serum Levels of Hs-CRP, CTnI and Blood Lipids in Patients with Coronary Heart Disease

ZHU Xu; ZHENG Li-ping

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Clinical Significance of Detecting Serum Levels of Hs-CRP, CTnI and Blood Lipids in Patients with Coronary Heart Disease

更新时间：2024-01-04

- Clinical Significance of Detecting Serum Levels of Hs-CRP, CTnI and Blood Lipids in Patients with Coronary Heart Disease
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 7, Pages: 258-260(2012)
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- Published：2012
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ZHU Xu, ZHENG Li-ping. Clinical Significance of Detecting Serum Levels of Hs-CRP, CTnI and Blood Lipids in Patients with Coronary Heart Disease[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 258-260.
DOI：

ZHU Xu, ZHENG Li-ping. Clinical Significance of Detecting Serum Levels of Hs-CRP, CTnI and Blood Lipids in Patients with Coronary Heart Disease[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 258-260. DOI：

摘要

目的: 研究冠心病患者血清超敏C反应蛋白(hs-CRP)、肌钙蛋白I(cTnI)、血脂水平变化及临床意义。方法: 对102例冠心病患者血清hs-CRP

cTnI

甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)和高密度脂蛋白(HDL-C)等生化指标水平进行检测

并与正常对照组的40例健康受试者进行比较分析。结果: SAP组血清hs-CRP水平显著高于正常对照组

差异具有统计学意义(P<0.05);UAP组、AMI组血清hs-CRP

cTnI

TG及LDL-C水平均显著高于正常对照组

HDL-C水平均显著低于正常对照组

差异均具有统计学意义(P<0.05);SAP组、UAP组血清hs-CRP

cTnI

TG及LDL-C水平均显著低于AMI组

HDL-C水平均显著高于AMI组

差异均具有统计学意义(P<0.05);SAP组血清hs-CRP

cTnI水平显著低于UAP组

差异亦均具有统计学意义(P<0.05);hs-CRP与TC

LDL-C均呈显著正相关(P<0.05)

与HDL-C均呈显著负相关(P<0.05)

hs-CRP与cTnI之间呈显著正相关(P<0.05)。结论: 检测冠心病患者血清hs-CRP

cTnI及血脂水平对患者疾病预测及治疗具有重要的临床意义。

Abstract

Objective: To study the clinical significance of detecting serum levels of high-sensitivity C-reactive protein(hs-CRP)

cardiac troponin I(cTnI) and blood lipids in patients with coronary heart disease (CHD). Method: The serum levels of hs-CRP

cTnI

triglycerides(TG)

total cholesterol(TC)

low-density lipoprotein(LDL-C)

high-density lipoprotein cholesterol(HDL-C) were detected in one hundred and two patients

and compared with those of 40 healthy subjects in the control group. Result: The serum level of hs-CRP in the stable angina pectoris(SAP) group was significantly higher than in the control group (P<0.05). The serum levels of hs-CRP

cTnI

LDL-C in the unstable angina pectoris(UAP) group and the AMI group were significantly higher than those in the control group (all P <0.05)

and the serum level of HDL-C was significantly lower than that in the control group (all P <0.05). The serum levels of hs-CRP

cTnI

LDL-C in the SAP group and the UAP group were significantly lower than those in the AMI group (all P <0.05)

and the serum levels of HDL-C in the SAP group and the UAP group were significantly higher than those in the AMI group (all P <0.05). The serum levels of hs-CRP

cTnI in the SAP group were significantly lower than those in the UAP group (all P <0.05). The serum level of hs-CRP was positively correlated with TC

LDL-C(P<0.05)

and was negatively correlated with HDL-C (P<0.05). The serum level of hs-CRP was positively correlated with cTnI (P<0.05). Conclusion: The detection of serum levels of hs-CRP

cTnI and blood lipids plays an important role in disease prediction and treatment of patients with CHD.

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