Comparative Study of Xiayuxue Decoction and Its Ingredients Recipe Against Porcine Serum Induced Liver Fibrosis in Rats
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Comparative Study of Xiayuxue Decoction and Its Ingredients Recipe Against Porcine Serum Induced Liver Fibrosis in Rats
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 1, Pages: 154-157(2012)
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Published:2012
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CHEN Shao-li, DU Guang-li, DING Na, et al. Comparative Study of Xiayuxue Decoction and Its Ingredients Recipe Against Porcine Serum Induced Liver Fibrosis in Rats[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(1): 154-157.
DOI:
CHEN Shao-li, DU Guang-li, DING Na, et al. Comparative Study of Xiayuxue Decoction and Its Ingredients Recipe Against Porcine Serum Induced Liver Fibrosis in Rats[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(1): 154-157.DOI:
Comparative Study of Xiayuxue Decoction and Its Ingredients Recipe Against Porcine Serum Induced Liver Fibrosis in Rats
Objective :To compare differences between Xiayuxue decoction and its ingredients recipe in inhibiting hepatic fibrosis. Method: Rat liver fibrosis model was duplicated with intraperitoneal injection of porcine serum. After 8 weeks of modeling
Xiayuxue decoction and its ingredients were administrated for 4 weeks
and at the end of 12 weeks
rats were sacrificed to obtain samples for determination of liver function and examination of liver histology. Result: Compared with model group
improvement in liver function and liver pathology were found in Xiayuxue diction group; Liver function and histology in Xiayuxue dection group was superior to that in its ingredients recipe group. Conclusion: The main action mechanism of Xiayuxue decoction and its ingredients recipe against liver fibrosis is in inhibiting immune response and protecting liver cells
and Xiayuxue decoction is superior to its ingredient recipe.