Objective: To observe the effects of Compound Kushen Injection on analgesia

hemostasis in mouse

and to observe to the anti-stress (induced by hypoxia and low temperature swimming) effect of the injection in tumor-bearing mice. Method: The hot plate method

the body-twisting method

capillary and broken tail method were used for evaluating the effects on analgesia and hemostasis accordingly

anti-stress effect of the injection was observed in the hepato-tumor-bearing mice. Result: Compared with controls

compound Kushen injection of 4

2

1 g·kg-1 could obviously increase the pain threshold for heat in mice

significantly extend the body-twisting incubation period and reduce the counting

obviously reduce the blood coagulation and bleeding time

and significantly prolong the hypoxia tolerance duration and low temperature swimming time in the tumor-bearing mice. Conclusion: Compound Kushen Injection has obvious analgesia and hemostatic effect

and can enhance the anti-stress ability in tumor-bearing mice.