Comparison of Content of Naringin, Neohesperidin, Total Flavonoid and Volatile Oil in Different Batches of and Quality Evaluation

WANG Yuan-qing; YAN Jian-ye; SHI Bai-mei; LI Shun-xiang; LUO Kun; WANG Lu; HUANG Hai-wei

您当前的位置：

首页 >

文章列表页 >

Comparison of Content of Naringin, Neohesperidin, Total Flavonoid and Volatile Oil in Different Batches of and Quality Evaluation

更新时间：2024-01-04

- Comparison of Content of Naringin, Neohesperidin, Total Flavonoid and Volatile Oil in Different Batches of and Quality Evaluation
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 7, Pages: 146-150(2012)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2012
- 稿件说明：
移动端阅览
WANG Yuan-qing, YAN Jian-ye, SHI Bai-mei, et al. Comparison of Content of Naringin, Neohesperidin, Total Flavonoid and Volatile Oil in Different Batches of and Quality Evaluation[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 146-150.
DOI：

WANG Yuan-qing, YAN Jian-ye, SHI Bai-mei, et al. Comparison of Content of Naringin, Neohesperidin, Total Flavonoid and Volatile Oil in Different Batches of and Quality Evaluation[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 146-150. DOI：

摘要

目的: 比较不同批次枳壳中柚皮苷、新橙皮苷、总黄酮、挥发油的含量

并评价其质量。方法: 高效液相色谱法

色谱柱为Diamonsil C18 (4.6 mm×250 mm

5 μm)

流动相乙腈-水 (20:80)(磷酸调pH至3.0);检测波长 283 nm

流速 1 mL·min-1

柱温30 ℃

测定柚皮苷和新橙皮苷;以柚皮苷为对照

采用紫外-可见分光光度法在283 nm处测定总黄酮;采用水蒸气蒸馏法提取测定挥发油含量;以柚皮苷含量、新橙皮苷含量、总黄酮含量、挥发油含量为综合评价指标

采用Topsis法评价其质量。结果: 柚皮苷含量范围在0%~6.12%

新橙皮苷含量在0%~4.55%

总黄酮含量在6.96%~18.99%

挥发油量在0.2%~2.0% (mL·g-1);17个批次样品质量差异较大。结论: 17批次枳壳中柚皮苷、新橙皮苷、总黄酮、挥发油的含量有较大差异;柚皮苷、新橙皮苷含量达到2010年版《中国药典》标准的仅6批

质量评价方法可行。

Abstract

Objective: To compare the content of naringin

neohesperidin

total flavonoids and volatile oil in different batches of Citrus aurantium and evaluate the quality. Method: The naringin and neohesperidin were detected by HPLC. The analytical column was a Diamonsil C18 (4.6 mm×250 mm

5 μm). A mixture of acetonitrile-water (pH was adjusted to 3.0 by phosphoric acid) (20: 80) was used as the mobile phase with the flow rate at 1 mL·min-1. The detection wavelength was set at 283 nm. The column temperature was set at 30 ℃. The UV spectrophotometry for the determination of total flavonoids is as follows: detection wavelength was at 283 nm

and the reference substance was naringin. The volatile oil was extracted by steam distillation. Topsis was employed for evaluating quality with the content of naringin

neohesperidin

total flavonoids and volatile oil. Result: The naringin

neohesperidin

total flavonoids and volatile oil were in the ranges of 0%-6.12%

0%-4.55%

6.96%-18.99% and 0.2%-2.0% (mL·g-1) respectively. The quality difference of the samples was large. Conclusion: The content difference of the naringin

neohesperidin

total flavonoids and volatile oil in 17 different batches of C. aurantium was large. The content of naringin and neohesperidin in 6 batches of C. aurantium comes up with 〈Chinese Pharmacopoeia 2010〉.The quality evaluation method was feasible.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Predictive Analysis of Quality Markers of Jiangxi Aurantii Fructus Based on Fingerprint and Network Pharmacology

Herbal Textual Research on Zingiberis Rhizoma Recens in Famous Classical Formulas and Its Quality Evaluation

HPLC Determination of Four Flavonoids of Aurantii Fructus Immaturus in Niuhuang Qingwei Pills and Genetic Analysis of Medicinal Materials

Determination of Content of Narigin and Hesperidin and Neohesperidin in Fructus Auranti Pieces by HPLC

Determination of Flavone Ingredients in Citrus Aurantium, Bitter Orange Immature, Walnut Peel and Tangerine Peel By Internal Standard Multi-control Method

Related Author

Hui WANG

Yanqing LIANG

Xingtai YU

Lu LIU

Jinxiang ZENG

Hongning LIU

Shouwen ZHANG

Jie GUO

Related Institution

Jiangxi University of Chinese Medicine，Research Center for Traditional Chinese Medicine Resources and Ethnic Minority Medicine

National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines， Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

Tianjin University of Traditional Chinese Medicine

Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co. Ltd.

Guangzhou Caizhilin Pharmaceutical Co. Ltd.

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰