Proteomics Study on Effects of Youguiyin Decoction on Kidney-Deficiency Syndrome in Mice
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Proteomics Study on Effects of Youguiyin Decoction on Kidney-Deficiency Syndrome in Mice
Chinese Journal of Experimental Traditional Medical FormulaeVol. 17, Issue 24, Pages: 109-114(2011)
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Published:2011
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LI Jun-li, LI Yun, LIU Ming-fu, et al. Proteomics Study on Effects of Youguiyin Decoction on Kidney-Deficiency Syndrome in Mice[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 109-114.
DOI:
LI Jun-li, LI Yun, LIU Ming-fu, et al. Proteomics Study on Effects of Youguiyin Decoction on Kidney-Deficiency Syndrome in Mice[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 109-114.DOI:
Proteomics Study on Effects of Youguiyin Decoction on Kidney-Deficiency Syndrome in Mice
Objective : To observe the effects of Youguiyin decoction on the mice with Kidney-Deficiency Syndrome in protein expression level. Method : Kunming male mice were randomly divided into three groups as follows: the kidney-deficiency model group
the Youguiyin group (5.6 g·kg-1 daily for 2 months)and the youth normal group. The proteins in liver
kidney
testis tissue and serum of the mice were separated and analysed by two-dimensional gel (2-DE) to find the proteins regulated and corrected by Youguiyin. These proteins were identified by mass spectrograph. Result : Tenty two regulated and corrected protein spots were detected
and 17 proteins spots were identified. Conclusion : This paper screens and identifies 17 proteins regulated and corrected by Youguiyin decoction.
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