FT-IR Characteristic Analysis of Gegenqinlian Decoction and its Active Components Alignments

XU Bei-lei; CUI Xiang-wei; SUN Su-qin; WEN Chun-xian; WANG Jing-juan; ZHANG Gui-jun; LIU Jing-jing; PENG Hui

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FT-IR Characteristic Analysis of Gegenqinlian Decoction and its Active Components Alignments

更新时间：2024-01-04

- FT-IR Characteristic Analysis of Gegenqinlian Decoction and its Active Components Alignments
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 18, Issue 7, Pages: 142-145(2012)
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- Published：2012
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XU Bei-lei, CUI Xiang-wei, SUN Su-qin, et al. FT-IR Characteristic Analysis of Gegenqinlian Decoction and its Active Components Alignments[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 142-145.
DOI：

XU Bei-lei, CUI Xiang-wei, SUN Su-qin, et al. FT-IR Characteristic Analysis of Gegenqinlian Decoction and its Active Components Alignments[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(7): 142-145. DOI：

摘要

目的: 研究葛根芩连汤及其药效组分的红外指纹表征

为建立复方组分指纹鉴定法提供科学依据。方法: 应用傅里叶红外光谱(Foruier transform infrared

FT-IR)进行测定

采用复方汤剂和化学药效组分指纹表征表述质量特征。结果: 葛根芩连汤的主要特征峰出现在1 727

1 614

1 509

1 448

1 362

1 272

1 031

838

767

582 cm-1等

安徽产区药材煎煮全方与道地药材煎煮全方的相似度最高。葛根芩连汤药效组分主要指纹表征(1 800~400 cm-1)有1 726

1 607

1 509

1 451

1 364

1 238

1 037

891

834

591 cm-1等。结论: 采用红外指纹表征鉴别法可评价葛根芩连汤的质量

可反映出本质的主要特征

具有明显的专属性。

Abstract

Objective: To study the foruier transform infrared(FT-IR) fingerprinting characteristics of Gegen Qinlian decoction and its active components alignments. Method: FT-IR was adopted to analyze and describe the characteristics by Gegen Qinlian decoction and the active components alignments. Result: The main characteristic peaks of Gegen Qinlian decoction are at 1 727

1 614

1 509

1 448

1 362

1 272

1 031

838

767

582 cm-1

etc.

and the crude drugs for decoction in Anhui region has the highest correlation coefficient with genuine medicinal materials. The FT-IR fingerprint characterization (1 800-400 cm-1) of the active components alignments for Gegen Qinlian decoction are 1 726

1 607

1 509

1 451

1 364

1 238

1 037

891

834

591 cm-1

etc. Conclusion: The FT-IR fingerprint identification method can be used for quality evaluation for Gegen Qinlian decoction

and reflect the main features. It has obvious specificity.

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