Effects of Soybean Flavone on Osteoporosis in Rats with Deficiency of the Kidney
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Effects of Soybean Flavone on Osteoporosis in Rats with Deficiency of the Kidney
Chinese Journal of Experimental Traditional Medical FormulaeVol. 18, Issue 5, Pages: 159-163(2012)
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Published:2012
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JIN Rui, WANG Shi-han, SUI Bo-wen, et al. Effects of Soybean Flavone on Osteoporosis in Rats with Deficiency of the Kidney[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(5): 159-163.
DOI:
JIN Rui, WANG Shi-han, SUI Bo-wen, et al. Effects of Soybean Flavone on Osteoporosis in Rats with Deficiency of the Kidney[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(5): 159-163.DOI:
Effects of Soybean Flavone on Osteoporosis in Rats with Deficiency of the Kidney
Objective: To observe effects of soybean flavone on osteoporosis in rats with deficiency of the kidney. Method: Female rats born 12 monthes were executed orariectomy to establish osteoporosis model. After 60 days
total flavonoids of soybean
with dose of 250
125
62.5 mg·kg-1
was ig given for 90 days. The content of ALP
Ca2+
P3-
Na+ estradiol(E2) in serum
the content of Ca2+
P3-
Na+
Mg2+in bones was measured
respectively. The bone density of tibia was messured. Result: The level of Ca2+
E2 of in serim was increased in total flavonoids 250
125 mg·kg-1 groups
but had no obvious effect on the content of P3-
Na+
ALP in blood; The content of Ca2+ in bones was increased
but had no obvious influence on Na+
Mg2+ in bones
meanwhile the bone density wa increasedd. Conclusion: Soybean flavone has effects on osteoporosis in rats with deficiency of the kidney